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an enzyme acting as a catalyst in the hydrolysis of an amide


(ˈæm ɪˌdeɪs, -ˌdeɪz)

an enzyme that catalyzes the hydrolysis of an acid amide.
References in periodicals archive ?
When first insect and mammalian PGRPs are cloned in 1998, it is noticed that they all contain an amidase homology domain (Brownell et al., 2016).
Besides, isoniazid is also hydrolyzed by amidase to toxic hydrazine.
Other studies have already found similar results and may be cohesive with the fact that an induction of this mechanism requires the participation of different molecules such as the regulatory protein AmpR, the permease AmpG, and homologs of the amidase. This process needs the presence of an inductive cofactor held by an amidase homologue, the anhydromuropeptide (3).
Moreover, these DEGs have 399 molecular functions (Figure S1B) wherein hydrolase, transport protein, transmembrane transporter activity, transferase activity, amidase transmembrane transporter, transcription factor activity, and efflux transmembrane transporter activity may be related to multidrug resistance in the MDR isolate strain of C.
The regulation of AmpC production has been historically understood to require three proteins: AmpG, a plasma membrane-bound permease; AmpD, a cytosolic peptidoglycan-recycling amidase; and AmpR, the transcriptional regulator of AmpC.
ampD encodes a cytosolic N-acetyl-anhydromuramyl-L-alanine amidase and specifically hydrolyzes the 1,6-anhydro-MurNAc peptide, thus inhibiting the ampC expression [11, 12].
Graber, "Amidase activity and thermal-stability of human thrombin," Applied Biochemistry and Biotechnology, vol.
Bacillus megaterium, a mesophilic bacterium, has been known as the important industrial microorganism for producing penicillin amidase, amylase, glucose dehydrogenase, and fungicidal and antiviral agents for a long time.
The lipoic acid bound to the food proteins and can be released by an intestinal amidase. Some bacteria encode an amidase called lipoamidasa capable of releasing lipoic acid from the intact 2-oxo acid dehydrogenase complexes.
Suresh et al., "Amidase, a cell wall hydrolase, elicits protective immunity against Staphylococcus aureus and S.
Identification of Amidase negative strains of Bacillus thuringiensis.