M2 PHARMA-August 9, 2019-Elicio Therapeutics Presents In Vivo Data for a Universal Amphiphile
Vaccine Targeting KRAS-Driven Cancers
FRIDAY, May 11, 2018 (HealthDay News) -- Self-assembling peptide amphiphile
(PA) nanofibers, incorporating an 18 amino acid sequence that retains the cholesterol efflux actions of apolipoprotein-A1 (apoA1) and a liver X receptor (LXR) agonist can target and treat atherosclerosis, according to an experimental study presented at the American Heart Association's Vascular Discovery: From Genes to Medicine Scientific Sessions 2018, held from May 10 to 12 in San Francisco.
Bioactive Peptide Amphiphile
Scaffolds to Enhance Spinal-Cord Regeneration
They have positive charge and are composed of amphiphile
molecule (having hydrophobic and hydrophilic regions) (GIULIANI et al., 2007).
A linear-hyperbranched supramolecular amphiphile
and its self-assembly into vesicles with great ductility.
Lu et al., "A POSS-based supramolecular amphiphile
and its hierarchical self-assembly behaviors," Macromolecular Rapid Communications, vol.
The Cu(II) ions in the metalloliposomes undergo reduction by one electron with glutathione and result in Cu(I) ions that trigger the decomposition of the amphiphile
and the vesicle.
These mostly amphiphile
compounds have been described to protect erythrocytes against hypotonic hemolysis .
[[GAMMA].sub.max] is the concentration difference between the interface and a virtual interface in the interior of the volume phase, while [A.sub.min] describes the minimum area of the amphiphile
molecules at the surfactant-saturated monolayer at the air/solution interface [58, 60].
Shao, "Self-assembly of a peptide amphiphile
based on hydrolysed Bombyx mori silk fibroin," Chemical Communications, vol.
Danielsson and Lindman  have correctly defined microemulsion as follows: "microemulsion is a system of water, oil and an amphiphile
(surfactant and co-surfactant) which is a single optically isotropic and thermodynamically stable liquid solution."
Due to the amphiphile
characteristics of soyasaponin Ab, it was hypothesized that TLRs might be involved in the stimulation of inflammatory pathways via NF-[kappa]B signalling, because TLRs are the most important receptors for antigen presenting cells to recognize conserved structures in microbe including those with amphiphile
structures (Kawai and Akira 2010).