Outcomes in these patients were poor, with prolonged hospital admissions and considerable mortality despite prolonged treatment with amphotericin
The patient was treated with intravenous amphotericin
B at a dose of 0.
LAS VEGAS -- An inhaled formulation of amphotericin
B in clinical development may answer the unmet need for antifungal prophylaxis in immunocompromised patients, said Michael J.
Tokyo, Japan, Apr 21, 2006 - (JCN) - Dainippon Sumitomo Pharma announced on April 20 that it has received approval for AmBisome for Injection 50mg, a liposomal formulation of the antifungal agent amphotericin
B, from the Ministry of Health, Labor and Welfare.
B, at a daily dose of 4 mg per kg body weight, was given by infusion on 6 consecutive days and repeated on days 14 and 21.
P boydii infections are difficult to treat due to amphotericin
B resistance and frequent need for surgical resection.
Nasdaq: BDSI; BDSIW) today announced it has licensed a topical formulation of its lead product, encochleated amphotericin
B to Accentia, Inc.
This action was based in part on the company's determination that the need for the Newark facility (which had served principally as the company's laboratory for the formulation development of Bioral Amphotericin
B) was no longer necessary now that Bioral Amphotericin
B is in clinical development in the U.
b lipid complex suspension for injection 5mg/ml, 2ml-20ml vial
Dr Kiran Tiwana, who was on her first week at Heartlands Hospital's oncology ward, is said to have confided in a colleague over her prescription, that led to the patients being given five times the normal dose of fungal infection drug Amphotericin
Dr Kiran Tiwana, who was on her first week at Heartlands Hospital's oncology ward, confided in a colleague over her prescription, that led to two cancer patients being given five times the normal dose of fungal infection drug Amphotericin
Of 133 patients initially treated with amphotericin
B, 80% were switched to another antifungal, and 38% of those responded.