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 (măk′rō-glô′sē-ə, -glŏs′ē-)
Enlargement of the tongue.

[French macroglossie : macro-, macro- + Greek glōssa, tongue.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
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Noun1.macroglossia - a congenital disorder characterized by an abnormally large tongue; often seen in cases of Down's syndrome
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n. macroglosia, agrandamiento excesivo de la lengua.
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References in periodicals archive ?
(4,6,7) Kyle and Bayrd reported that 26% of patients with multiple myeloma exhibited amyloid macroglossia. (3) Others have reported cases of oral amyloidosis that occurred as a result of multiple myeloma.
In the literature, surgical reduction of the tongue has been suggested in cases of amyloid macroglossia. (4,9,24,25) Kerner et al treated such patients by performing midline edge glossectomy; their patients healed well and enjoyed an improved quality of life as a result of the restoration of their ability to speak and eat.