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Related to anaplasia: metaplasia


Reversion of cells to an immature or a less differentiated form, as occurs in most malignant tumors.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(Biology) reversion of plant or animal cells to a simpler less differentiated form
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014


(ˌæn əˈpleɪ ʒə, -ʒi ə)

the loss of structural differentiation within a cell or group of cells.
[1905–10; ana- + -plasia]
an`a•plas′tic (-ˈplæs tɪk) adj.
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.anaplasia - loss of structural differentiation within a cell or group of cells often with increased capacity for multiplication, as in a malignant tumoranaplasia - loss of structural differentiation within a cell or group of cells often with increased capacity for multiplication, as in a malignant tumor
dysplasia - abnormal development (of organs or cells) or an abnormal structure resulting from such growth
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.


n. anaplasia, falta de diferenciación en las células.
English-Spanish Medical Dictionary © Farlex 2012
References in periodicals archive ?
When grading was based on the features of anaplasia, 83.3% showed a favourable histology, whereas in 16.7% the histology was unfavourable.
The designation of anaplasia in PA and the characterization of anaplastic PA as a distinct variant or a different entity entirely remain highly controversial.
and with the degree of anaplasia. The hypoxia inducible factor (HIF-1)
(34,59) Type 2 papillary RCC is characterized by pseudostratified high-grade epithelium with abundant eosinophilic cytoplasm and nuclear anaplasia (Figure 6, A and B).
A avaliacao microscopica revelou uma proliferacao de celulas epiteliais com discreta anaplasia, distribuidas em pequenas formacoes tubulo papilares e com grandes formacoes cisticas (Figura 2 A e B).
The lower section of the follicles, namely the hair follicles and the hair bulb part that is below the bulge, experiences morphological changes, such as growth, anaplasia, and diapause.
Tumour cells in OSA typically demonstrate severe anaplasia and pleomorphism and may be epitheloid, plasmacytoid, fusiform, small, and round or spindled.
Histologically, the neoplasm is composed of mature spindleform fibroblasts with a rich collagenous component, with a variable mitotic index but no evidence of cellular anaplasia or abnormal mitoses [4].
Mitoses were conspicuous, and there was no anaplasia or significant pleomorphism.
These lesions reveal a smooth muscle phenotype with low mitotic activity, limited vascularization and lacks of anaplasia and necrosis [4-8, 10-13].
There was no evidence of large cell changes, significant cytological anaplasia, or desmoplasia.
Se constato el adelgazamiento de la capsula con algunos centros germinales evidentes, obliteracion de los senos medulares que se hallan infiltrados con celulas neoplasicas, igualmente se encontro un grado severo de anaplasia, con perdida de la relacion nucleo-citoplasma (1:2,5), anisocitosis severa, hipercromatismo nuclear, cromatina dispersa, nucleolos muy evidentes; se observan dos y hasta tres nucleolos por nucleo, asi como de 8 a 10 mitosis en 10 campos de 40x y abundante presencia de macrofagos al interior de la neoplasia.