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Related to aneuploidy: aneuploidy screening, Turner syndrome


Having a chromosome number that is not a multiple of the haploid number for the species.
A cell or an organism characterized by an aneuploid chromosome number.

an′eu·ploi′dy (-ploi′dē) n.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.aneuploidy - an abnormality involving a chromosome number that is not an exact multiple of the haploid number (one chromosome set is incomplete)
abnormalcy, abnormality - an abnormal physical condition resulting from defective genes or developmental deficiencies
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
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References in periodicals archive ?
Study of aneuploidy and DNA fragmentation in gametes of patients with severe teratozoospermia.
* Qualitative fluorescence PCR (QF-PCR): Detection of aneuploidy (such as Down syndrome) and repeat expansion diseases (such as Fragile X and Huntington's disease).
All pregnant women considered to have increased risk factors or, less commonly, to be anxious about pregnancy should be offered a prenatal diagnostic test for the confirmation of fetal chromosome aneuploidy. (1) The most common numerical variations of chromosomes recognized in prenatal samples are 13, 18, or 21 trisomies and sex chromosome aneuploidies, representing approximately 70% of all chromosomal anomalies detected.
Prequel Prenatal Screen with expanded aneuploidy analysis can potentially improve birth outcomes by identifying more pregnancies at risk for birth defects and syndromes, as well as those at risk for pregnancy complications due to these chromosome changes in the placenta.
Spectrum[R] preimplantation genetic screening for aneuploidy (PGT-A) from Natera, Inc, has demonstrated that it improves in vitro fertilization (IVF) results for all women, including those of advanced maternal age, announces Natera.
Detection rates for aneuploidy by first-trimester and sequential screening.
DNA repair errors are responsible for a variety of birth defects as well as conditions like Down syndrome or Turner syndrome that result from an incorrect number of chromosomes in an individual, also called aneuploidy.
The researchers note that the clinical adoption of cfDNA sequencing for chromosomal aneuploidy screening has already had a global effect.
He said, "a few recent studies have shown that embryo aneuploidy (chromosome abnormality preventing embryo implantation or causing miscarriage) changes with age in a u-shaped curvilinear regression, declining steadily before age 30 and increasing steadily thereafter.
However, rapid aneuploidy testing methods such as fluorescent in situ hybridization (FISH), quantitative fluorescence-polymerase chain reaction (QF-PCR), and multiplex probe ligation assay (MLPA) are also routinely used for prenatal diagnosis in the laboratory (4).
Although not yet approved by the FDA, prenatal genomic screening for aneuploidy has been extensively validated worldwide.
Unfertilized oocyte karyotyping after IVF has disclosed two leading mechanisms for the origin of aneuploidy. The first is homologues chromosome segregation towards the same axis during meiosis I, leading to disomic or nulisomic daughter cells.