angiogenesis inhibitor


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Related to angiogenesis inhibitor: tumor angiogenesis

angiogenesis inhibitor

n.
A drug that blocks angiogenesis in cancerous tissue, thus interfering with tumor growth or metastasis.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.angiogenesis inhibitor - a drug that is designed to prevent the growth of blood vessels that nourish tumors
medicament, medication, medicinal drug, medicine - (medicine) something that treats or prevents or alleviates the symptoms of disease
References in periodicals archive ?
Scientists made the discovery after studying cilengitide, an experimental angiogenesis inhibitor which has not yet been licensed for patients.
Tokyo, Japan, Mar 31, 2006 - (JCN) - OncoTherapy Science and Fuso Pharmaceutical Industries jointly announced on March 29 that the Pharmaceuticals and Medical Devices Agency (PMDA) has accepted a notification of the phase I clinical trial plan of OTS102, an angiogenesis inhibitor currently under development by OncoTherapy Science.
Her paper, "Angiogenesis Inhibitors Endostatin or TNP-470 Reduce Intimal Neovascularization and Plaque Growth in Apolipoprotein e-Deficient Mice," showed that the growth of the small blood vessel network feeding coronary artery plaques in mice could be reduced by giving them an angiogenesis inhibitor.
Folkman notes, however, that autopsies find small, previously undiscovered prostate tumors in nearly half of men over 50 who die of other causes, suggesting that some natural force - perhaps an angiogenesis inhibitor - has held the tumors in check.
Interviewed payers from Brazil report that patient performance status is a key determinant in deciding which patients have access to angiogenesis inhibitors, and that there is a "one-out one-in system" in INCA (National Cancer Institute of Brazil) hospitals in which likely candidates must wait for another patient to stop therapy before being considered for treatment with an angiogenesis inhibitor.
The drug is an angiogenesis inhibitor, operating much like the drugs that have received widespread publicity in recent days, angiostatin and endostatin.
This is a very potent angiogenesis inhibitor," Folkman says.