Causes of death were dissecting aortic aneurysm, hepatic angiosarcoma
, acute myeloid leukemia, and pulmonary embolism in a patient with cholangiocarcinoma that had metastasized to the peritoneum.
Athenex announced preliminary data showing early clinical responses in the first part of a two part study of Oraxol monotherapy in patients with unresectable cutaneous angiosarcoma
. To date, 10 patients have been enrolled in the clinical study, which is being conducted in four sites in the U.S.
Stewart--Treves syndrome (STS) is a type of cutaneous angiosarcoma
that develops in the setting of chronic lymphedema.
The vascular channels were irregular, anastomosing, and sinusoidal, with pleomorphic lining cells showing frequent mitotic figures and focal necrosis, corresponding to angiosarcoma
. In view of immunohistochemistry, it expressed positive endothelial markers CD31 and erythroblast transformation-specific (ETS)-related gene (ERG) oncoprotein [Figure 1], also corresponding to angiosarcoma
, but negative for calretinin, actin, desmin, CD68, human melanoma black 45, S-100, and CK.
The main differential diagnoses of PHE include epithelioid sarcoma, epithelioid hemangioendothelioma, and epithelioid angiosarcoma
is a rare malignant vascular tumor of older adults that most often involves the scalp and skin and is associated with high rates of local recurrence and distant metastases.
A patient from an angiosarcoma
support group commented, "I went for more than 30 years without meeting another person [with angiosarcoma]." (3) Thus, these groups are able to provide a sanctuary for the patient who otherwise would be forever isolated from any other person living with their particular disease.
Peritoneal histology was of higher grade than the prostate tumor, resembling epithelioid angiosarcoma
Nasal Region treated with Radiation Therapy: Case Report
Histopathological examination showed that the tumor was an angiosarcoma
containing hemorrhagic and necrotic areas that were infiltrating the adrenal cortex (Figure 3).
, primary, metastatic, central nervous system, pathology, neuroimaging