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Agonizing physical or mental pain; torment. See Synonyms at regret.
v. an·guished, an·guish·ing, an·guish·es
To cause to feel or suffer anguish.
To feel or suffer anguish.

[Middle English angwisshe, from Old French anguisse, from Latin angustiae, distress, from angustus, narrow; see angh- in Indo-European roots.]
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Extraordinarily painful or distressing:
References in periodicals archive ?
The anguishing but rather rearguard horror of Bhopal (though, yes, it must be acknowledged that evil, like rust, never sleeps) gives way to a visit to Angkor Wat and an upsetting replay of the demonic Pol Pot regime in Cambodia.
Disclosing a harm-causing medical error can be one of the most anguishing conversations a healthcare professional can have," said Banja.