Abnormalities found exclusive to experimental groups are as follows: Craniostenosis, short snout, anophthalmia
, microphthalmia, exophthalmia, palpabral coloboma, kyphosis, lordosis, spina bifida, prognathia, scoliosis, limb malrotation and deformation, clinodactyly, ectrodactyly, apodia, ankylodactyly, fused digits, flexed paw and hooked tail, at 44g/g B.
20] Kiley et al and Konstantinova have reported associated anomalies like tracheo-oesophageal fistula, cleft lip, anencephaly, anophthalmia
The morphological observations of fetuses showed anomalies like open eye lid, distorted body axis, kyphosis, skin hemorrhage, drooping wrist, microphthalmia, low set arm, kinky tail, exencephaly anophthalmia
, maxillary macrognathia, microcephaly, clubbed foot and microtia.
Records indicated that he had bilateral anophthalmia
with no light perception.
Tests revealed he had no eyeballs - a condition called anophthalmia
that affects just a handful of children every year in the UK.
These visual impairment disorders include retinitis pigmentosa, keratoconus, cataract, nystagmus, astigmatism, glaucoma, microphthalmia, anophthalmia
, strabismus and myopia.
Daisy has anophthalmia
, which affects just one in 10,000 babies in the UK.
Learning disability multiple disabilities) Visual diagnosis Bilateral anophthalmia
Optic nerve hypoplasia Visual acuity No light perception No light perception (O.
microphthalmia and anophthalmia
and up to 20% have an identifiable
Fourteen different anomalies were recorded, of which agnathia, microcepahaly, microphthalmia, anophthalmia
, short neck and omphalocelle showed gradual increase in the percentage anomalies with the treatment of low to higher concentration of insecticide and observed with all applied concentrations.
and microphthalmia have been reported in rats exposed during organogenesis to verteporfin at 40 times the dose used in humans.
Other ocular diseases, such as Leber's hereditary optic neuropathy or anophthalmia
, are classified as rare, and as such are not as attractive for research and development funding as many of the more common diseases.