[4,5] Many antiasthmatic
drugs (inhaled or oral medicine) are available in the market, but these drugs are expensive and may have adverse effects.
The studies conducted showed the antibacterial, anti-inflammatory immunomodulator, gastroprotective antiviral (11), antiasthmatic
(17), antidiabetic (18), antihelminthic (19), antifungal (20), antitumoral (21), antihistaminic (22) effects of the nigella sativa.
effect of Nigella sativa in airways of asthmatic patients.
(9) The leaves contain triterpene ixorene, (10) ixorapeptide I, ixorapeptide II, (11) and quercitrin, (12) and have cardioprotective, (13) antinociceptive, (14) antioxidant, (15) antidiarrhoeal, (16) antiasthmatic
, (17) hypoglycaemic, and hypolipidemic activity, (18) and the roots show antioxidant activity.
Fisetin has been documented to have antioxidant, anticarcinogenic, antiulcer, anticonvulsant, anti-hyperlipidemic, antiarthritic, antidiabetic, antimicrobial, antiviral, cardioprotective, and neuroprotective properties.16-22 Recently, researchers have also reported the antiasthmatic
potential of fisetin against OVA-induced airway hyperresponsiveness via inhibition of lgG, lgE, iNOS, TNF-[alpha], IL-4, IL-5, IL-13, and NF-kB.19,23 As immune-inflammatory reactions like AR and asthma are two closely related disorders of airway disease, almost 88% of asthma patients have suffered from the symptoms of AR as well.24 Moreover, the animal models of both the allergic inflammation diseases are produced similarly.24
effects of hesperidin, a potential Th2 cytokine antagonist, in a mouse model of allergic asthma." Mediators Inflamm.
Patients with asthma used antiasthmatic
medication when needed.
This compound has been demonstrated to possess several biological activities including immunomodulatory, antioxidant, antiasthmatic
, anticarcinogenic, antipyretic, anti-inflammatory, antiulcer, antidepressive, and antiamoebic activities .
These flavonoid compounds have diverse biological functions, such as flower coloring, UV light protection, auxin transport, defense, allelopathy, anticancer, antiasthmatic
, anti-inflammatory, and antimicrobial activities [5, 15-17].
Backer, "The use of antiasthmatic
medication among Danish elite athletes," Ugeskrift for Laeger, vol.
Atta-ur-Rahman and co-workers, have exhibited exciting biological activities including anti-oxidant, anti-leishmanial, anti-AIDS, immunomodulating, antiasthmatic
, analgesic, nematicidal and anti-cancer activities.