anticholinesterase


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Related to anticholinesterase: anticholinesterase drugs

an·ti·cho·li·nes·ter·ase

 (ăn′tē-kō′lə-nĕs′tə-rās′, -rāz′, ăn′tī-)
n.
A substance that inhibits the activity of a cholinesterase, especially acetylcholinesterase.

anticholinesterase

(ˌæntɪˌkɒləˈnɛstəˌreɪz)
n
(Biochemistry) any of a group of substances that inhibit the action of cholinesterase

an•ti•cho•lin•es•ter•ase

(ˌæn tiˌkoʊ ləˈnɛs təˌreɪs, -ˌreɪz, -ˌkɒl ə-, ˌæn taɪ-)

n.
an enzyme or drug that blocks the action of acetylcholinesterase, thereby increasing the stimulating effect of acetylcholine on the muscles.
[1950–55]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.anticholinesterase - a medicine that inhibits cholinesterase by combining with it and so has a cholinergic effect
medicament, medication, medicinal drug, medicine - (medicine) something that treats or prevents or alleviates the symptoms of disease
neostigmine, Prostigmin - a cholinergic drug (trade name Prostigmin) used to treat some ophthalmic conditions and to treat myasthenia gravis
References in periodicals archive ?
Grob, "Adverse cardiovascular effects of anticholinesterase medications," American Journal of the Medical Sciences, vol.
The seven-year-old female patient presented in this case report had failed initial treatment with anticholinesterase and had undergone monthly intravenous immunoglobulin (IVIG) for nearly one year when she developed myasthenic crisis necessitating mechanical ventilation.
AD patients receiving pharmacological treatment with anticholinesterase agents (such as Donepezil) have been excluded from this study, due to the likely effect of these drugs on the PFR.
In fact, the treatment of AD symptoms related to cognitive decline is based on anticholinesterase activity modulation.
The species that exhibited the best antioxidant activity in the three tests and anticholinesterase activity was H.
Anticholinesterase was given to reverse neuromuscular block at the end of procedure with injection neostigmine 0.04-0.07 mg/ kg body weight I/V in combination with injection glycopyrrolate 5-10 micrograms/kg body weight I/V.
Although many patients with MuSK-MG are presently treated with anticholinesterase inhibitors or immunosuppressants, such patients do not generally respond adequately to these treatments, added the company.
In clinical practice, atropine, a nonselective muscarinic receptor blocker, is employed to prevent the parasympathomimetic effects induced by neostigmine when the anticholinesterase agent is clinically used to reverse the blockage of neuromuscular transmission caused by non-depolarizing muscular relaxants (Barrio, Miguel, Garcia, & Pelegrin, 2007).
These toxins constituents at higher concentration or at high does affect the membrane disruption activity that affect digestive functionality and anticholinesterase activity of the CNS (Central Nervous System) when exposed in mammals.
Other causes of prolonged paralysis following the administration of succinylcholine include a quantitative deficiency of the pseudocholinesterase enzyme' overdose of succinylcholine' liver disease' prior use of magnesium sulfate or anticholinesterase drugs' and the presence of significant metabolic or electrolyte abnormalities.
From the assay evaluation, the final purified ChE procedure displayed the highest sensitivity of detecting the anticholinesterase namely mercury, copper, malaoxon and carbofuran compared to the impure ChE and the results were further discussed in detail to the potential application of ChE from P.
Anticholinesterase poisoning in Turkey-clinical, laboratory and radiologic evaluation of 269 cases.