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The Group's revenue increased overall primarily due to the significant growth of the anticancer agent Lenvima mainly accompanying the acquisition of approval for use in the treatment of hepatocellular carcinoma in Japan, as well as the steady growth of fully human anti-TNF-a monoclonal antibody Humira and antiepileptic agent Fycompa, absorbing the impact of drug pricing revision in Japan and the launch of generic versions of antiemetic agent Aloxi in the United States.
Repeated administration of the novel antiepileptic agent levetiracetam does not alter digoxin pharmacokinetics and pharmacodynamics in healthy volunteers.
Thus, it is necessary to investigate for an antiepileptic agent that is highly efficacious as well as safe in items of drug-related toxicity.
Rash is the most common adverse reaction of this antiepileptic agent and the most common reason for treatment discontinuation as it can be life-threatening.
Besides, in 40 SUDEP cases, 38 (95%) patients underwent toxicological analysis and no antiepileptic agent was detected in 21 (55.3%) of these.
These symptoms were similar to those associated with a previous episode of clustered seizures that happened four years ago, at which point she was prescribed an antiepileptic agent, Levetiracetam.
Food and Drug Administration (FDA) for an indication expansion regarding the use of its in-house developed antiepileptic agent Fycompa (perampanel hydrate) as an adjunctive treatment of primary generalized tonic-clonic (PGTC) seizures in patients with epilepsy 12 years of age and older.
INTRODUCTION: Phenytoin seems to be the most commonly used and studied antiepileptic agent and its side effects and toxicity symptoms are well documented.(1) It is a well-known fact that phenytoin may commonly cause central nervous system side effects like sedation, blurring of vision, nystagmus, ataxia, hyperkinesia, psychosis and phenytoin encephalopathy.
Lamotrigine: an antiepileptic agent for the treatment of
They found that a ketogenic diet reduces seizures in mice by decreasing expression of the protein Adk, which is responsible for clearing the natural antiepileptic agent adenosine from the brain.
Lamictal (lamotrigine) is an antiepileptic agent developed by Burroughs Wellcome Co.