People with Alzheimer's disease who used antiepileptic drugs
had a higher number of accumulated hospital days than people with Alzheimer's disease who did not use antiepileptics, according to a new study from the University of Eastern Finland.
"We launched Arvelle to bring truly innovative CNS products to patients suffering from serious neurological conditions and cenobamate is the perfect first pipeline product," said Mark Altmeyer, chief executive officer of Arvelle/'Given the data generated in clinical trials and the FDA acceptance of the NDA, we believe cenobamate has the potential to be an important antiepileptic drug
treatment option for adult patients suffering from partial-onset seizures.
Cenobamate is a novel and small molecule investigational antiepileptic drug
that is being developed to treat partial-onset seizures in adult patients.
were found to be linked with almost ninefold increased odds for two adverse skin reactions, Steven-Johnson syndrome and toxic epidermal necrolysis, compared with non-AED medication classes in an analysis of data from the Food and Drug Administration Adverse Event Reporting System (FAERS).
According to another recent study from the same research group, people with Alzheimer's use antiepileptic drugs
more often than those without the disease.
The association of antiepileptic drug
use with dementia was investigated in a sample from a large German statutory health insurance provider, Allgemeine Ortskrankenkasse (AOK).
In a study carried out in UK Southampton General Hospital, to investigate nonadherence to antiepileptic drug
treatment among patients with epilepsy in secondary care and the associations between adherence and seizure control, perceptions of illness and medication, anxiety and depression, of 54 patients, 59% were estimated to be nonadherent to medication.
Long-term antiepileptic drug
therapy contributes to the acceleration of atherosclerosis.
Despite these limitations, the results are notable because they represent the only data set yet reported from a community-based source large enough to allow analysis of the many clinical variables that play into the potential interactions between various contraceptive types, various antiepileptic drug
classes, and the diverse number of epilepsy subtypes, he said.
Fycompa is a first-in-class antiepileptic drug
discovered and developed by Eisai.
Early child development and exposure to antiepileptic drugs
prenatally and through breastfeeding: a prospective cohort study on children of women with epilepsy.
Valproic acid (VPA), a broad-spectrum antiepileptic drug
, has been used in therapy for epilepsy since 1967.