Resistance to echinocandin-class
antifungal drugs. Drug Resist Updat.
Food & Drug Administration (FDA) for treating some of the most drug-resistant forms of tuberculosis (TB).A The new drug was approved under the Limited Population Pathway for Antibacterial and
Antifungal Drugs (LPAD pathway) as part of a three-drug, six-month, all-oral regimen for the treatment of people with extensively drug-resistant TB (XDR-TB) or multidrug-resistant TB (MDR-TB) who are treatment-intolerant or non-responsive (collectively "highly drug-resistant TB").
CorMedix announced that Phoebe Mounts, EVP and general counsel, presented at a public meeting on July 12, 2019 hosted by FDA discussing the Limited Population Pathway for Antibacterial and
Antifungal Drugs. In her presentation, Dr.
Currently, only three major classes of clinical
antifungal drugs exist.
Following the passage of the limited population pathway for antibacterial and
antifungal drugs established by the 21st Century Cures Act the FDA can now grant approval for some anti-infective products on the basis of limited clinical data.
auris is often resistant to major
antifungal drugs that are typically used to treat such infections.
In vitro antifungal activity of topical and systemic
antifungal drugs against Malassezia species.
Arikayce (amikacin liposome inhalation suspension) is the first drug to be approved under the Limited Population Pathway for Antibacterial and
Antifungal Drugs, or LPAD pathway, established by Congress under the 21st Century Cures Act.
Arikayce is the first medication approved under the FDA's Limited Population Pathway for Antibacterial and
Antifungal Drugs, or LPAD pathway, which encourages development and approval of antibacterial and
antifungal drugs to treat certain serious or life-threatening infections.
Data regarding costs of
antifungal drugs, hospital, and ICU stay were provided by each participant hospital for each patient.
Meanwhile an increase in the emergence of new pathogenic species difficult to diagnose and treat has been observed (Coleman et al., 2008); this increase is not only due to the frequent use of
antifungal drugs to treat these kinds of infections but also due to therapeutic drug overdose.