receptor

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Related to antigen receptor: monoclonal antibody

re·cep·tor

 (rĭ-sĕp′tər)
n.
1. Physiology A specialized cell or group of nerve endings that responds to sensory stimuli.
2. Biochemistry A molecular structure or site on the surface or interior of a cell that binds with substances such as hormones, antigens, or neurotransmitters or is activated by events such as a change in the concentration of an ion.

receptor

(rɪˈsɛptə)
n
1. (Physiology) physiol a sensory nerve ending that changes specific stimuli into nerve impulses
2. any of various devices that receive information, signals, etc

re•cep•tor

(rɪˈsɛp tər)

n.
1. a protein molecule, usu. on the surface of a cell, that is capable of binding to a complementary molecule, as a hormone, antibody, or antigen.
2. a sensory nerve ending or sense organ that is sensitive to stimuli.
[1900–05]

re·cep·tor

(rĭ-sĕp′tər)
1. A nerve ending specialized to sense or receive stimuli. Skin receptors respond to stimuli such as touch and pressure and signal the brain by activating portions of the nervous system. Receptors in the nose detect odors.
2. A cell structure or site that is capable of combining with a hormone, antigen, or other chemical substance.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.receptor - a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological responsereceptor - a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response
anatomical structure, bodily structure, body structure, complex body part, structure - a particular complex anatomical part of a living thing; "he has good bone structure"
alpha receptor, alpha-adrenergic receptor, alpha-adrenoceptor - receptors postulated to exist on nerve cell membranes of the sympathetic nervous system in order to explain the specificity of certain agents that affect only some sympathetic activities (such as vasoconstriction and relaxation of intestinal muscles and contraction of smooth muscles)
beta receptor, beta-adrenergic receptor, beta-adrenoceptor - receptors postulated to exist on nerve cell membranes of the sympathetic nervous system in order to explain the specificity of certain agents that affect only some sympathetic activities (such as vasodilation and increased heart beat)
2.receptor - an organ having nerve endings (in the skin or viscera or eye or ear or nose or mouth) that respond to stimulationreceptor - an organ having nerve endings (in the skin or viscera or eye or ear or nose or mouth) that respond to stimulation
lateral line, lateral line organ - sense organs of fish and amphibians; believed to detect pressure changes in the water
organ - a fully differentiated structural and functional unit in an animal that is specialized for some particular function
enteroceptor, interoceptor - any receptor that responds to stimuli inside the body
exteroceptor - any receptor that responds to stimuli outside the body
pineal eye, third eye - a sensory structure capable of light reception located on the dorsal side of the diencephalon in various reptiles
baroreceptor - a sensory receptor that responds to pressure
chemoreceptor - a sensory receptor that responds to chemical stimuli
thermoreceptor - a sensory receptor that responds to heat and cold
eye, oculus, optic - the organ of sight
ear - the sense organ for hearing and equilibrium
organ of hearing - the part of the ear that is responsible for sensations of sound
inner ear, internal ear, labyrinth - a complex system of interconnecting cavities; concerned with hearing and equilibrium
semicircular canal - one of three tube loops filled with fluid and in planes nearly at right angles with one another; concerned with equilibrium
stretch receptor - a receptor in a muscle that responds to stretching of the muscle tissue
papilla - a small nipple-shaped protuberance concerned with taste, touch, or smell; "the papillae of the tongue"
sensory system - the body's system of sense organs
effector - an organ (a gland or muscle) that becomes active in response to nerve impulses
Translations

receptor

[rɪˈseptəʳ] N (Physiol, Rad) → receptor m

receptor

[rɪˈsɛptər] n (ANATOMY)récepteur m

receptor

n
(= nerve)Reizempfänger m, → Rezeptor m
(Rad) → Empfänger m

receptor

[rɪˈsɛptəʳ] nrecettore m

re·cep·tor

n. receptor, terminación nerviosa que recibe un estímulo y lo transmite a otros nervios;
auditory ______ auditivo;
contact ______ de contacto;
mechanoreceptormecanoreceptor;
chemoreceptorquimoreceptor;
proprioceptive ______ propioceptivo;
sensory ______ sensorial;
taste ______ gustativo;
temperature ______ de temperatura.

receptor

n receptor m; estrogen receptor-positive positivo para receptores de estrógeno
References in periodicals archive ?
Food and Drug Administration has cleared the Company's Investigational New Drug application for FT596, the Company's first off-the-shelf chimeric antigen receptor natural killer cell cancer immunotherapy which targets multiple tumor-associated antigens.
The United States Food and Drug Administration (FDA) has granted orphan drug designation to China-based CARsgen Therapeutics Inc's investigational CAR-T cell therapy fully human anti-BCMA BCMA (B Cell Maturation Antigen) autologous chimeric antigen receptor (CAR) T Cells (ct053) intended for the treatment of multiple myeloma, it was reported on Friday.
10,370,452 covering compositions and uses of effector T cells expressing a chimeric antigen receptor (CAR), where such T cells are derived from a pluripotent stem cell including an induced pluripotent stem cell (iPSC).
Chimeric antigen receptor T-cell (CAR-T) therapy boosts a patient's own immune cells to fight cancer and can cost hundreds of thousands of dollars, the Associated Press reported.
Modern breakthroughs in treatment such as the use of chimeric antigen receptor cells - CAR-T - may help cancer sufferers but not others, that is a cruel reality.
PRGN-3006 UltraCAR-T is an autologous chimeric antigen receptor T (CAR-T) cell therapy under investigation for the treatment of patients with relapsed or refractory acute myeloid leukemia (AML) or higher risk myelodysplastic syndrome (MDS) (clinical trial identifier: NCT03927261).
Another 23 articles include updates on such matters as antigen receptor function in the context of the nanoscale organization of the B cell membrane, the antibody response of Plasmodium falciparum: cues for vaccine design and the discovery of receptor-based antibiotics, double-stranded RNA sensors and modulators in innate immunity, new molecular insight into immune cell development, and the gut microbiota regulation of T cells during inflammation and autoimmunity.
The company added that PRGN-3005 is a first-in-class investigational therapy using autologous chimeric antigen receptor T (CAR-T) cells is the second candidate to clear IND utilising its transformative UltraCAR-T platform that reduces manufacturing time to less than two days following non-viral gene transfer.
Anti-CD19 chimeric antigen receptor (CAR) T-cell therapy is an effective new therapy for patients with aggressive B-cell malignancies including leukaemia and lymphoma.
Hong Kong-based biotechnology company EXUMA has acquired all rights to novel chimeric antigen receptor T (CAR-T) cell therapy and manufacturing assets for the development and commercialisation of cellular therapies in Greater China to be used in the treatment of solid tumor malignancies, the company said.
T-cells can be genetically engineered to express a chimeric antigen receptor (CAR) that recognizes the B-cell antigen CD19.2 CD19 is expressed on developing and mature B-cells, absent on pluripotent haematopoietic stem cells and highly retained over the process of neoplastic transformation.
NHS England has secured a landmark deal with the manufacturers of Tisagenlecleucel - a form of chimeric antigen receptor T-Cell (CAR-T) therapy that has been shown to cure some patients with B cell acute lymphoblastic leukaemia.