antigen

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Related to antigen receptors: B cell receptors

an·ti·gen

 (ăn′tĭ-jən) also an·ti·gene (-jēn′)
n.
A molecule that is capable of binding to an antibody or to an antigen receptor on a T cell, especially one that induces an immune response. An antigen is usually a foreign substance, such as a toxin or a component of a virus, bacterium, or parasite.

an′ti·gen′ic (-jĕn′ĭk) adj.
an′ti·gen′i·cal·ly adv.
an′ti·ge·nic′i·ty (-jə-nĭs′ĭ-tē) n.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

antigen

(ˈæntɪdʒən; -ˌdʒɛn) or

antigene

n
(Biochemistry) a substance that stimulates the production of antibodies
[C20: from anti(body) + -gen]
ˌantiˈgenic adj
ˌantiˈgenically adv
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

an•ti•gen

(ˈæn tɪ dʒən, -ˌdʒɛn)

n.
1. any substance that can stimulate the production of antibodies and combine specifically with them.
2. any commercial substance that, when injected or absorbed into animal tissues, stimulates the production of antibodies.
3. antigens of a particular type collectively.
[1905–10; anti (body) + -gen]
an`ti•gen′ic, adj.
an`ti•gen′i•cal•ly, adv.
an`ti•ge•nic′i•ty (-dʒəˈnɪs ɪ ti) n.
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.

an·ti·gen

(ăn′tĭ-jən)
A substance that stimulates the production of an antibody when introduced into the body. Antigens include toxins, bacteria, viruses, and other foreign substances. See Note at blood type.
The American Heritage® Student Science Dictionary, Second Edition. Copyright © 2014 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

antigen

A molecule recognized as foreign by the body’s immune system, causing the release of antibodies.
Dictionary of Unfamiliar Words by Diagram Group Copyright © 2008 by Diagram Visual Information Limited
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.antigen - any substance (as a toxin or enzyme) that stimulates an immune response in the body (especially the production of antibodies)
substance - a particular kind or species of matter with uniform properties; "shigella is one of the most toxic substances known to man"
immunizing agent, immunogen - any substance or organism that provokes an immune response (produces immunity) when introduced into the body
immunology - the branch of medical science that studies the body's immune system
agglutinogen - any substance that acts as an antigen to cause agglutinin production
fetoprotein, foetoprotein - any of several antigens that occur naturally in the fetus and sometimes in adults with cancer
anatoxin, toxoid - a bacterial toxin that has been weakened until it is no longer toxic but is strong enough to induce the formation of antibodies and immunity to the specific disease caused by the toxin; "diphtheria toxoid"
antigenic determinant, epitope, determinant - the site on the surface of an antigen molecule to which an antibody attaches itself
Rh, Rh factor, rhesus factor - a blood group antigen possessed by Rh-positive people; if an Rh-negative person receives a blood transfusion from an Rh-positive person it can result in hemolysis and anemia
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
Translations
antigen
antigeeni
antigén
antígeno
antigen
antigen

antigen

[ˈæntɪdʒən] Nantígeno m
Collins Spanish Dictionary - Complete and Unabridged 8th Edition 2005 © William Collins Sons & Co. Ltd. 1971, 1988 © HarperCollins Publishers 1992, 1993, 1996, 1997, 2000, 2003, 2005

antigen

[ˈæntɪdʒən] nantigène manti-hero antihero [ˈæntihɪərəʊ] nantihéros m
Collins English/French Electronic Resource. © HarperCollins Publishers 2005

antigen

nAntigen nt
Collins German Dictionary – Complete and Unabridged 7th Edition 2005. © William Collins Sons & Co. Ltd. 1980 © HarperCollins Publishers 1991, 1997, 1999, 2004, 2005, 2007

antigen

[ˈæntɪdʒən] nantigene m
Collins Italian Dictionary 1st Edition © HarperCollins Publishers 1995

an·ti·gen

n. antígeno, sustancia tóxica que estimula la formación de anticuerpos;
carcinoembriogenic ______ carcinoembriogénico.
English-Spanish Medical Dictionary © Farlex 2012

antigen

n antígeno; carcinoembryonic — antígeno carcinoembrionario; prostate-specific — (PSA) antígeno prostático específico (APE)
English-Spanish/Spanish-English Medical Dictionary Copyright © 2006 by The McGraw-Hill Companies, Inc. All rights reserved.
References in periodicals archive ?
Natural Killer Cells Engineered with Chimeric Antigen Receptors Enhance And-tumor Activity.
Chimeric Antigen Receptors (CARs) and Adoptive Immune System
Abken, "Adoptive immunotherapy with genetically engineered T cells: modification of the IgG1 Fc 'spacer' domain in the extracellular moiety of chimeric antigen receptors avoids 'off-target' activation and unintended initiation of an innate immune response," Gene Therapy, vol.
NK cells engineered with chimeric antigen receptors can be targeted to tumors with high specificity.
Additionally, NK cells engineered with chimeric antigen receptors can be targeted to tumours with high specificity.
The companies will engineer immune cells with fully human chimeric antigen receptors (CARs) and T-cell receptors (TCRs) directed to disease-specific cell surface antigens to enable the precise killing of tumor cells.
They discuss molecular targets in cancer, cancer nanomedicine, T-cell chimeric antigen receptors, cancer drug resistance, RNA interference-based therapeutics, targeting RNA with small molecules, the cellular thermal shift assay, genome editing, 26S proteasome inhibitors, biobanking, mitochondrial biogenesis as a pharmacological target, triclosan as an environmental toxicant, and G protein-coupled receptors and retinal degenerative disorders.
Scientists screened specially bred genetically engineered mice for the targeting molecules, known as chimeric antigen receptors or Cars.
Juno intends to use The Trianni Mouse with its proprietary high throughput, single cell sequencing technology and direct-to-CAR screening to rapidly identify fully-human binders for conversion to chimeric antigen receptors in its engineered T cell programs.
Cell Medica, in collaboration with strategic partners, is developing a range of products using three proprietary technology platforms including activated T cells, chimeric antigen receptors and engineered T cell receptors.
Beatty et al., "T cells expressing chimeric antigen receptors can cause anaphylaxis in humans," Cancer Immunology Research, vol.