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Related to antimetabolite: methotrexate
A substance that closely resembles an essential metabolite and therefore inhibits physiological reactions involving that metabolite.
an′ti·met′a·bol′ic (-mĕt′ə-bŏl′ĭk) adj.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
(Pharmacology) any drug that acts by disrupting the normal growth of a cell. Sulfonamide drugs are antimetabolites and some antimetabolites are used in cancer treatment
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
an•ti•me•tab•o•lite(ˌæn ti məˈtæb əˌlaɪt, ˌæn taɪ-)
any substance that interferes with growth by competing with a nutrient metabolite for receptors or enzymes in the body, used esp. for treating certain cancers.
an`ti•met`a•bol′ic (-ˌmɛt əˈbɒl ɪk) adj.
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
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|Noun||1.||antimetabolite - an antineoplastic drug that inhibits the utilization of a metabolite|
antineoplastic, antineoplastic drug, cancer drug - any of several drugs that control or kill neoplastic cells; used in chemotherapy to kill cancer cells; all have unpleasant side effects that may include nausea and vomiting and hair loss and suppression of bone marrow function
fluorouracil - an antimetabolite used to treat certain cancers
mercaptopurine, Purinethol - a drug (trade name Purinethol) that interferes with the metabolism of purine and is used to treat acute lymphocytic leukemia
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