antimitotic


Also found in: Medical.
Related to antimitotic: antiemetic, colchicine, telangiectasia

an·ti·mi·tot·ic

 (ăn′tē-mī-tŏt′ĭk, ăn′tī-)
adj.
Preventing or interfering with mitosis.
n.
An antimitotic drug.

antimitotic

(ˌæntɪmaɪˈtɒtɪk)
adj
acting against mitosis
n
a drug which acts against mitosis

an•ti•mi•tot•ic

(ˌæn ti maɪˈtɒt ɪk, -mɪ-, ˌæn taɪ-)

adj.
1. of or pertaining to a substance capable of arresting the process of cell division.
n.
2. an antimitotic substance.
[1965–70]
Translations
References in periodicals archive ?
8: Supply of coronary stenting for bifurcation siding with PCI and coronary stents coated with cobalt-chrome antimitotic substance;
G2-M arrest and antimitotic activity mediated by Casticin, a flavonoid isolated from Viticis Fructus (Vitex rotundifolia linne fil.
First, to what extent does the antimitotic effect of chlorpyrifos extend to its major metabolites, chlorpyrifos oxon, the active inhibitor of cholinesterase, or trichloropyridinol, the catabolic product that is prominent in fetal brain after maternal chlorpyrifos exposure (24), which has been identified almost ubiquitously in urine samples of U.
P2 "in toto" and the single components were characterized for antioxidant capacity, antimitotic activity on MCF-7 human breast cancer cells and for toxicity to human lymphocytes and macrophages.
Some studies performed with antimitotic substances showed us that increase in chromosome number and endomitosis of the cell causes the formation of MN.
Etoposide and other podophyllotoxin derivatives are used from their antineoplastic or antimitotic properties, they affect the nervous and gastro-intestinal systems.
tumefaciens-induced tumors (or Crown Gall) in potato disc tissue is an assay based on antimitotic activity and can detect a broad range of known and novel antitumor effects (McLaughlin and Rogers, 1998).
Kobayashi H, Namikoshi M, Yoshimoto T, Yokochi T (1996) A screening method for antimitotic and antifungal substances using conidia of Pyricularia oryzae, modification and application to tropical marine fungi.
The ligans and other chemical moieties present in it have demonstrated antitumour activity while podophyllotoxin and several other related compounds have manifested antimitotic activity and capability of inhibiting DNA, RNA and protein synthesis (Singh and Shah, 1994).
Because the cells were not pretreated with an antimitotic agent, morphology was only evident in some chromosomes.
For example, paclitaxel with hyaluronic acid 10-12 kDa components for antimitotic delivery in bladder carcinoma cells has been reported.