In terms of the o-coumaric acid, phloridzin, protocatechuic acid, vanillic acid, rutin and quercetin contents which have antifungal and
antimutagen properties, it was seen that the changes varied in the range of 0.34-2.57 mg 100 ml-1, 1.18-6.12 mg 100 ml-1, 0.04-0.11 mg 100 ml-1, 0.04-0.24 mg 100 ml-1, 1.01-5.16 mg 100 ml-1 and 0.05-0.16 mg 100 ml-1 (Table 6).
Hydroxychavicol: a new phenolic
antimutagen from betel leaf.
Szumiel, "Effects of an
antimutagen of 1,4-dihydropyridine series on cell survival and DNA damage in L5178Y murine sublines," Nukleonika, vol.
[140.] Dar SA (2015) Mutagenic Effects of Endosulfan in Crucian Carp (Carassius carassius L.) and the Role of Podophyllum hexandrum Royle as an
Antimutagen. PhD thesis, University of Kashmir, Srinagar, India.
It is an excellent source of phenolic compounds, antioxidants, and
antimutagen [5].
In addition,
antimutagen [46], antioxidation, and angiotensin-converting enzyme inhibition activities of kimchi are thought to protect against disease [47].
Even among
antimutagen compounds, great care should be taken because a number of substances reported to be
antimutagens or anticarcinogens have been shown to be mutagenic or carcinogenic themselves (Zeiger, 2003).
(1998) and Perez & Gago (2006) demonstrated the ability of natural
antimutagen including lettuce extracts to reduce the mutagenic activity of potassium dichromate and Benz[a]pyrene in male Balb/C mice.
Resveratrol, a natural compound found in grapes (and also in mulberries, peanuts, blueberries, bilberries, cranberries, some pines, and the roots of Japanese knotweed) appears to protect against cancer, cardiovascular and other diseases by acting as an antioxidant,
antimutagen, antiviral, neuroprotective and anti-inflammatory agent.
"White tea was a much more powerful
antimutagen than green tea," reports Oregon's Gilberto Santana-Rios, a coauthor of the study.
The term "
antimutagen" was originally used to denote an agent that reduced the apparent yield of mutations - spontaneous or induced.