antiporter


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antiporter

(ˈæntɪˌpɔːtə)
n
(Biology) biology a membrane protein that transports substances across cell membranes
References in periodicals archive ?
It has been known that the cystine/glutamate antiporter is a plasma membrane-bound protein critically involved in glutamatergic transmission.
VAChT is an antiporter, which utilises the proton gradient generated by ATPase, transporting one acetylcholine molecule for two proton (figure 1) (NGUYEN et al, 1998).
The ATPases generate a proton electrochemical gradient across the vacuolar membrane Na+/H+ antiporter, to compartmentalize Na+ into the vacuole (Chinnusamy et al.
AX09 is a virus-like particle that displays a portion of the extracellular domain of the cystine-glutamate antiporter system protein xCT (SLC7A11), which has been found to be overexpressed in cancer stem cells which have unique biological properties that represent a key cellular reservoir for relapse, metastatic progression, and therapeutic resistance.
In serpentine-intolerant Arabidopsis thaliana, an induced loss of function mutation in the [Ca.sup.2+]- [H.sup.+] antiporter, CAX1, enhances survival on soils with a low calcium to magnesium ratio (Bradshaw, 2005).
Skulachev, "Participation of ATP/ADP antiporter in oleate- and oleate hydroperoxide-induced uncoupling suppressed by GDP and carboxyatractylate," Biochimica et Biophysica Acta, vol.
According to one recent study, glutamate inhibits the xCT glutamatecystine antiporter, leading to intracellular cysteine depletion.
Magnesium efflux involves several exchanges including [Na.sup.+]/[Mg.sup.2+], [Ca.sup.2+]/[Mg.sup.2+], [Mn.sup.2+]/[Mg.sup.2+] antiporter, and [Cl.sup.-]/[Mg.sup.2+] cotransporter [13].
Using the purified YiiP protein, zinc efflux occurs via a [Zn.sup.2+]/[H.sup.+] antiporter [44].
System xc(-) cystine/ glutamate antiporter: an update on molecular pharmacology and roles within the CNS.