TDZ, [C.sub.8][H.sub.13][N.sub.3][O.sub.4]S, which is 1-(2-ethyl sulfonyl ethyl)-2-methyl-5-nitro-imidazole derivative, an antiparasitic drug, is used as an antiprotozoal drug
(molecular weight: 247.273 g/ mol).
Chloroquine is an antiprotozoal drug
primarily used in malaria which has much less side effects and cost as compared to antimony compounds.
Thus, inhibition of the biosynthetic steps of protozoal glycolipids is emerging as a realistic target for antiprotozoal drug
discovery (McConville, 1995).
Said-Fernondez, "A new vial microassay to screen antiprotozoal drugs
," Pharmacologyonline, vol.
Structurally related antiprotozoal drugs
, namely, nitroimidazole derivatives including metronidazole (MNZ), secnidazole (SNZ), tinidazole (TNZ), ornidazole (ONZ), and metronidazole benzoate (MB), etc., are a class of veterinary drugs and are used widely as antibacterial and antiprotozoan drugs in poultry and swine dysentery .
The cases most frequently involved analgesic and non-steroidal anti-inflammatory drugs (n=373, 25.2%); antiepileptic, antipsychotic, psychoactive, and anxiolytic drugs (n=229, 16.3%); antihistamine, asthma, flu, and cough drugs (n=157, 12.0%); and antibiotic, anti-fungal; and antiprotozoal drugs
ABSTRACT: The present study was carried out to determine the incidence rate of the Trypanosomiasis in Thari camels and observe the efficacy of various antiprotozoal drugs
. Five hundred camels were observed for the identification of trypanosomiasis by using blood smears (three thin and three thick blood smears from each animal) prepared from different localities of district Therparker.
Phillipson, "Natural products and the development of selective antiprotozoal drugs
," Phytotherapy Research, vol.
cruzi at higher doses, as well as to evaluate the combination of different doses of the extract with specific antiprotozoal drugs
(i.e., benznidazol) to determine whether any of these therapeutic options can result in a better response allowing the removal of the parasite.
Phillipson, "Natural products as sources of antiprotozoal drugs
," Current Opinion in Anti-Infective Investigational Drugs, vol.