antithrombin


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Related to antithrombin: heparin, Antithrombin deficiency

antithrombin

(ˌæntɪˈθrɒmbɪn)
n
biochem a substance that counteracts the action of thrombin, preventing the formation of blood clots
References in periodicals archive ?
There was no difference in most treatment details; however, gabexate was significantly used in the control group, and antithrombin III was significantly used in the rTM group.
[USPRwire, Wed Jul 17 2019] Thrombosis drugs help in the prevention or inhibition of thrombus, by mimicking the role of antithrombin, a protein molecule produced in the body, which helps clotting of the blood.
Normal distribution of quantitative variables (protein C, protein S, antithrombin III, DD, FDPs, CRP, hs-CRP, WBC count, procalcitonin) was evaluated using Kolmogorov-Smirnow Z (K - S) test.
Amongst the 18 tested for an underlying thrombophilia, four (40.0%) had protein C deficiency, five (50.0%) had protein S deficiency, and two (33.3%) had antithrombin deficiency.
Two concurrent chromosomal aberrations involving interstitial deletion in 1q24.2q25.2 and inverted duplication and deletion in 10q26 in a patient with stroke associated with antithrombin defciency and a patent foramen ovale.
Inherited antithrombin deficiency Type IIb alters what and results in what?
They express antithrombin resistance conferring a major susceptibility to thrombosis ([4,5]).
Acutely ill patients may have an antithrombin deficiency, resulting in an inaccurately low aPTT and undue coagulation (Zehnder, Price, & Jin, 2012).
Application of Antithrombin III Is the Best Anticoagulation Strategy for Splenectomy.
In a cohort study containing three cohorts of families with a hereditary deficiencies of protein C, protein S, and antithrombin III, compared with nondeficient family members, subjects with protein S or protein C deficiency but not antithrombin III deficiency had a higher risk for arterial thromboembolism before 55 years of age that was independent of their history of prior venous thromboembolism [4].
pseudomallei infection, leading to depletion of the natural endothelial modulators protein C, protein S, and antithrombin [10,11].
Antithrombin is a natural anticoagulant that inhibits thrombin (factor IIa), factor Xa, and other serine proteases in the coagulation cascade.