antithrombin


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Related to antithrombin: heparin, Antithrombin deficiency

antithrombin

(ˌæntɪˈθrɒmbɪn)
n
biochem a substance that counteracts the action of thrombin, preventing the formation of blood clots
References in periodicals archive ?
Annualized market data for the critical care market, including the individual markets for factor XIII concentrate, fibrinogen concentrate, antithrombin, prothrombin complex concentrate and albumin from 2006 to 2012, with forecasts provided up to 2019.
Patients with antithrombin deficiency or homozygous FVL need life long anticoagulation after a first VTE event due to high recurrence risk.
This is now required for a recombinant technology used to develop transgenic animals, such as the goats that produce recombinant antithrombin.
The antithrombin assay uses a chromogenic method and follows similar manufacturer instructions.
The mechanisms involved in thrombosis development induced by genetic risk factors discovered so far can be summarized in two groups: (6) 1) Decreased control of thrombin generation: activated protein C resistance (due to Factor V Leiden or other causes), prothrombin mutation (20210), elevated factor VIII level, and deficiencies of proteins C and 5; or 2) Decreased neutralization of thrombin: antithrombin deficiency.
This represents the largest known cohort of pregnant patients with HD treated with antithrombin for the prevention of VTE during a high-risk situation," Dr.
Antithrombin (Recombinant) and its remarkable growth over the past year," stated rEVO Biologics President Yann Echelard, Ph.
of Framingham said regulators cleared its drug ATryn, which is manufactured using milk from goats that have been scientifically altered to produce extra antithrombin,
Tokyo, Japan, July 21, 2005 - (JCNN) - Mitsubishi Pharma (TSE: 4509) announced July 20 that its overseas subsidiary Mitsubishi Pharma Europe of London received approval to market argatroban, Mitsubishi Pharma's proprietary selective antithrombin agent, as of June 1 and put it on sale on July 15.
The work-up should also include a prothrombin time/partial thromboplastin time and lupus anticoagulant profile in all of its manifestations; a measurement of protein C, S, and antithrombin III levels; a check for activated protein C resistance; as well as use of Markers of Coagulation and Hemostasis Activation (MOCHA) or your laboratory's equivalent in looking for prothrombin fragment 1.
The model was applied to the test results for plasma antithrombin activity, a routine assay frequently used in the hemostasis laboratory, over the period 1996-1999.
Other recent Genzyme Transgenics patents include the right to produce antibodies at commercial levels in the milk of transgenic animals and to produce recombinant human antithrombin III in the milk of goats.