antithrombin


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Related to antithrombin: heparin, Antithrombin deficiency

antithrombin

(ˌæntɪˈθrɒmbɪn)
n
biochem a substance that counteracts the action of thrombin, preventing the formation of blood clots
References in periodicals archive ?
Inherited antithrombin deficiency Type IIb alters what and results in what?
They express antithrombin resistance conferring a major susceptibility to thrombosis ([4,5]).
In the present study we observed decrease in antithrombin levels with advancement of fibrosis.
Antithrombin was assayed on citrated plasma using a commercial automated amidolytic antithrombin assay (Coamatic Antithrombin, diaPharma, West Chester, Ohio).
Patients with antithrombin deficiency or homozygous FVL need life long anticoagulation after a first VTE event due to high recurrence risk.
ATryn is the first transgenically produced therapeutic protein and the first recombinant antithrombin approved in the United States.
This is now required for a recombinant technology used to develop transgenic animals, such as the goats that produce recombinant antithrombin.
The approval of ATryn marks a significant milestone in the development of this innovative recombinant technology and delivers a new therapeutic option to benefit hereditary antithrombin deficient patients who are undergoing surgery or childbirth procedures," said Geoffrey F.
This report confirms the greater risk of VTE in women with protein S, protein C, or antithrombin deficiency, compared with unaffected women.
In August 2006, ATryn, GTC's recombinant form of human antithrombin, was approved by the European Commission for use in patients with hereditary antithrombin deficiency undergoing surgical procedures.
The 14th edition adds entries on antithrombin deficiency and ovarian hyperstimulation syndrome.