Headquartered in Madrid, PharmaMar is a biopharmaceutical company, focused on oncology and committed to research and development which takes its inspiration from the sea to discover molecules with antitumor
In these settings, MEN1309/OBT076 showed substantial in vitro antitumor
The Phase 1b clinical trial, being conducted by BeiGene, is an open-label, dose-escalation and expansion study to investigate the safety, pharmacokinetics and antitumor
activity of PD-0325901 in combination with lifirafenib in patients with advanced or refractory solid tumors that harbor RAS mutations, RAF mutations and other MAPK pathway aberrations.
Summary: This study identifies potential antitumor
compounds from a series of new stigmasterol derivatives.
This markedly enhances the frequency of a vast range of immune effectors, including lymphocytes expressing gd heterodimer receptors, which possess a potent anti-infectious and antitumor
competence," the authors write.
The poster titled "TLR9 agonist SNA-induced innate and adaptive immune responses in tumor microenvironment enhance checkpoint inhibitor antitumor
activity in mouse tumor models" supports the ongoing clinical development of the company's proprietary SNA technology and highlights its potential impact in the tumor microenvironment in potentiating antitumor
effects of anti-PD-1.
(Activity: Anthelmintic, Analgesic), 2- Adenium obesum (Activity: Antitumor
, Antimicrobial), 3- Aegle marmelos (Activity: Anti-diabetic, Anti-inflammatory), 4- Ageratum Sp.
It is suggested that PGE2 signals through EP4 receptors may suppress the antitumor
activity of immune cells.
To date, the immunotherapeutic antitumor
effect of bacteria has been proven in the genus Bifidobacterium, Clostridium, Listeria, Escherichia, and Salmonella [10, 11].
In addition, SIMFO has launched preclinical studies on cannabinoid antitumor
activity and drug development utilising Cannabics Pharmaceuticals' proprietary cannabinoid formulations.
In the article titled "Epstein-Barr Virus-Induced Gene 3 (EBI3) Blocking Leads to Induce Antitumor
Cytotoxic T Lymphocyte Response and Suppress Tumor Growth in Colorectal Cancer by Bidirectional Reciprocal-Regulation STAT3 Signaling Pathway" , there were errors in the title, Introduction, Materials and Methods, and the legend of Figure 2, which should be corrected as follows: