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Defective development resulting in the absence of all or part of an organ or tissue.


(Pathology) pathol congenital absence or abnormal development of an organ or part
[C19: New Latin, from a-1 + -plasia, from Greek plassein to form]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.aplasia - failure of some tissue or organ to develop
dysplasia - abnormal development (of organs or cells) or an abnormal structure resulting from such growth


n. aplasia, falta de desarrollo normal en un órgano.
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References in periodicals archive ?
The present study reports a case of the left lateral SCC (LSCC) aplasia.
Anaemia in our patients was generally mild to moderate in severity (haemoglobin >7 g/dl) except in a patient with co-existing acute leukaemia and another with pure red cell aplasia, in whom it was severe.
Two patients in the ipilimumab arm died from toxicities related to therapy, one from marrow aplasia, and one from colitis.
A clinical diagnosis of aplasia cutis congenita was made.
1) Between 30-67% of patients with sickle cell disease (SCD) get infected causing transient red cell aplasia (TRCA), otherwise called aplastic crisis.
The most notorious initial and powerful signs appeared in the finding of Santenseen and his colleagues in Sweden in 1896, when the first cases of death by benzene exposure were identified in four workers in the bicycle tire industry, who developed bone marrow aplasia by exposure to a solvent containing elevated concentrations of benzene (4).
Viene dado por una agenesia o aplasia de los nucleos de los nervios craneales VI (nervio abducens) y VII (nervio facial) que son los mas frecuentemente involucrados, pero otros nervios craneales pueden estar involucrados tambien, lo que provoca paralisis facial y estrabismo convergente.
1,2] JS is an autosomal recessive neurodevelopmental disorder, characterized by molar tooth malformation, a complex brainstem malformation that reflects aplasia and marked hypoplasia of cerebellar vermis, thickened and elongated superior cerebellar peduncles, and deepened interpeduncular fossa that is apparent on axial magnetic resonance imaging (MRI) at the midbrain-hindbrain junction.
A total of 7 radiologically distinct inner ear malformations were detected in 19 (23%) children including sclerotic cochlea as a sequela of meningitis (n=6), Mondini deformity (n=3), cochlea dysplasia (n=3), large vestibular aqueduct syndrome (LVAS) (n=3), large internal auditory canal (n=2), semicircular canal aplasia (n=1), and semicircular canal dysplasia (n=1).
Aplastic anemia is a hematologic condition that results in pancytopenia and is characterized by bone marrow hypoplasia or aplasia.
The nine-year-old had his leg amputated because of a rare condition called tibial aplasia.