aplastic anemia

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Related to aplastic anemia: Fanconi anemia

aplastic anemia

A condition in which the bone marrow fails to generate adequate numbers of new red blood cells, white blood cells, and platelets. It can be caused by a genetic disorder, infection, exposure to radiation or toxic chemicals, or other factors.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

a•plas′tic ane′mia

(eɪˈplæs tɪk)

severe anemia due to depressed functioning of the bone marrow, usu. resulting from bone cancer, radiation, or the toxic effects of drugs or chemicals.
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.aplastic anemia - anemia characterized by pancytopenia resulting from failure of the bone marrowaplastic anemia - anemia characterized by pancytopenia resulting from failure of the bone marrow; can be caused by neoplasm or by toxic exposure
anemia, anaemia - a deficiency of red blood cells
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References in periodicals archive ?
Aplastic anemia leaves a person at higher risk of infections and uncontrolled bleeding.
(Tokyo: 4151, President and CEO: Masashi Miyamoto, 'Kyowa Hakko Kirin') announced today that it has received the partial change approval of Romiplate (code name: AMG531, generic name: romiplostim (recombinant), 'the drug') for an additional indication of treatment of aplastic anemia (AA) in patients who have had an inadequate response to conventional therapy from Japan's Ministry of Health, Labour and Welfare (MHLW).
NiCord is also being evaluated in a Phase 1/2 clinical study in patients with severe aplastic anemia.
After she was admitted to Alberta Children's Hospital she was diagnosed with Aplastic Anemia - a rare and serious disease in which the bone marrow fails to produce enough blood cells.
Novartis oncology global drug development head, Samit Hirawat, said, 'Promacta is a promising medicine that, if approved for first-line use in severe aplastic anemia, may redefine the standard of care for patients with this rare and serious bone marrow condition.
Kadia, "Updates on the pathophysiology and treatment of aplastic anemia: a comprehensive review," Expert Review of Hematology, vol.
Aplastic anemia is a very common disease of the blood system, but it is also one of the severe case in hematopoietic system, its incidence showed an increasing trend.
After his diagnosis was confirmed with bone marrow aspiration and biopsy as aplastic anemia with bone marrow cellularity of <10% and without any evidence of dysplasia, 1 mg/kg steroid and 5 mg/kg cyclosporin were started.
* A review of the Aplastic Anemia products under development by companies and universities/research institutes based on information derived from company and industry-specific sources.
The HemaXellerate clinical trial aims to recruit 10 patients with aplastic anemia that have not shown material signs of improvement under the current the standard of care.
A comparison clinical study of two aplastic anemia treatments found that ATGAM, currently the only licensed aplastic anemia drug in the United States, improved blood cell counts and survival significantly more than Thymoglobulin, a similar but reportedly more potent treatment.
The patient in your report has been defined as severe pancytopenic but the criteria used for severe aplastic anemia is the presence of two out of following three; neutrophil count less than 200 cells/microliter, platelet count less than 20.000 cells/microliter and corrected reticulocyte count of less than 1%.