aplastic anemia


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Related to aplastic anemia: Fanconi anemia

aplastic anemia

n.
A condition in which the bone marrow fails to generate adequate numbers of new red blood cells, white blood cells, and platelets. It can be caused by a genetic disorder, infection, exposure to radiation or toxic chemicals, or other factors.

a•plas′tic ane′mia

(eɪˈplæs tɪk)

n.
severe anemia due to depressed functioning of the bone marrow, usu. resulting from bone cancer, radiation, or the toxic effects of drugs or chemicals.
[1930–35]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.aplastic anemia - anemia characterized by pancytopenia resulting from failure of the bone marrowaplastic anemia - anemia characterized by pancytopenia resulting from failure of the bone marrow; can be caused by neoplasm or by toxic exposure
anemia, anaemia - a deficiency of red blood cells
References in periodicals archive ?
Novartis oncology global drug development head, Samit Hirawat, said, 'Promacta is a promising medicine that, if approved for first-line use in severe aplastic anemia, may redefine the standard of care for patients with this rare and serious bone marrow condition.
This phase II clinical study, involving 74 patients, is significant because it suggests that a stem cell transfusion can be used to treat aplastic anemia that is non-responsive to first-line therapies.
Bone marrow transplants have increased the survival rate of patients with aplastic anemia.
Diagnosis in patients with severe pancytopenia suspected of having aplastic anemia.
Additionally, the report provides an overview of key players involved in therapeutic development for Aplastic Anemia and features dormant and discontinued projects.
Aplastic anemia is more common in male than the female11.
In the present study, among young adults, aplastic anemia 11 cases (45.
Objective: The objective of this study was to determine the frequency of cure with cyclosporin therapy in patients with aplastic anemia.
Studies in Philippines24 and Nepal25 reported that males were affected with Aplastic anemia much more frequently then females, which might be a result of higher incidence of occupational exposure to chemicals and of pesticides exposure as a common etiological agent for Aplastic anemia in these countries.
After his diagnosis was confirmed with bone marrow aspiration and biopsy as aplastic anemia with bone marrow cellularity of <10% and without any evidence of dysplasia, 1 mg/kg steroid and 5 mg/kg cyclosporin were started.
A snapshot of the global therapeutic scenario for Aplastic Anemia.
The HemaXellerate clinical trial aims to recruit 10 patients with aplastic anemia that have not shown material signs of improvement under the current the standard of care.