apoptosis


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ap·op·to·sis

 (ăp′əp-tō′sĭs, ăp′ə-tō′-)
n.
A natural process of self-destruction by degradative enzymes in certain cells, such as epithelial cells and erythrocytes, that are genetically programmed to have a limited lifespan or are damaged, as by irradiation or toxic drugs. Also called programmed cell death.

apoptosis

(ˌæpəpˈtəʊsɪs)
n
(Biology) biology the programmed death of some of an organism's cells as part of its natural growth and development. Also called: programmed cell death
[C20: from Greek: a falling away, from apo- + ptōsis a falling]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.apoptosis - a type of cell death in which the cell uses specialized cellular machinery to kill itself; a cell suicide mechanism that enables metazoans to control cell number and eliminate cells that threaten the animal's survival
cell death, necrobiosis - (physiology) the normal degeneration and death of living cells (as in various epithelial cells)
Translations
References in periodicals archive ?
Ovarian follicular atresia and postovulatory regression in mammals is mediated by apoptosis, which is a natural occurring cause of cellular death.
Cell Death: Apoptosis and Other Means to an End, 2nd Edition
Background: Oxidized low-density lipoprotein (ox-LDL)-induced oxidative stress and endothelial apoptosis are essential for atherosclerosis.
A recent study confirmed the role of PC that could induce apoptosis in adipocyte cell culture (11), so PC alone might be developed into a safer lipolytic agent that causes less necrosis, and thus less inflammation and side effects.
Objective: To examine the HCV genotype 3a specific effects on caspases involved in apoptosis, expression levels of caspases-3, 8, 9, and 10 in peripheral blood mononuclear cells (PBMCs) of HCV genotype 3a infected patients.
The initiation of cell cycle arrest, apoptosis and autophagy are the important strategies in cancer treatment as well as prevention.
Flow cytometry was used to identify the amount of apoptosis. SPSS 15 was used to analyse the data.
Previous studies have shown that [beta] cell apoptosis and dysfunction are significantly increased in patients and animals with type 2 diabetes [1-3].
This review will summarize recent evidences in the field of STING-mediated cell death (including apoptosis and necrosis) and discuss relevant clinical significance.
Macrophages fulfill a broad range of functions in phagocytosis, microbial killing, host defense, tissue homeostasis and repair, pathology and development, and their proliferation; migration and apoptosis have been emerged as important therapeutic targets for a variety of human diseases [1, 2].
In addition, whether miR-378 regulates the apoptosis of bovine granulosa cells (bGCs) remains undetermined.
Currently most anti-cancer therapies (chemotherapy, radiation and immunotherapy) work by killing cancer cells through a process called apoptosis, which activates proteins called caspases, leading to cell death.