solubility

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sol·u·bil·i·ty

 (sŏl′yə-bĭl′ĭ-tē)
n. pl. sol·u·bil·i·ties
1. The quality or condition of being soluble.
2. The amount of a substance that can be dissolved in a given amount of solvent.

solubility

(ˌsɒljʊˈbɪlɪtɪ)
n, pl -ties
1. (Chemistry) the ability of a substance to dissolve; quality of being soluble
2. (Chemistry) a measure of this ability for a particular substance in a particular solvent, equal to the quantity of substance dissolving in a fixed quantity of solvent to form a saturated solution under specified temperature and pressure. It is expressed in grams per cubic decametre, grams per hundred grams of solvent, moles per mole, etc

sol•u•bil•i•ty

(ˌsɒl yəˈbɪl ɪ ti)

n.
the quality or property of being soluble; relative capability of being dissolved.
[1670–80]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.solubility - the quantity of a particular substance that can dissolve in a particular solvent (yielding a saturated solution)
definite quantity - a specific measure of amount
solution - a homogeneous mixture of two or more substances; frequently (but not necessarily) a liquid solution; "he used a solution of peroxide and water"
2.solubility - the property (of a problem or difficulty) that makes it possible to solve
property - a basic or essential attribute shared by all members of a class; "a study of the physical properties of atomic particles"
insolubility, unsolvability - the property (of a problem or difficulty) that makes it impossible to solve
3.solubility - the quality of being soluble and easily dissolved in liquid
quality - an essential and distinguishing attribute of something or someone; "the quality of mercy is not strained"--Shakespeare
insolubility - the quality of being insoluble and difficult to dissolve in liquid
Translations
liukoisuus
løselighet

solubility

[ˌsɒljʊˈbɪlɪtɪ] Nsolubilidad f

solubility

n
(of problem)Lösbarkeit f

solubility

[ˌsɒljʊˈbɪlɪtɪ] nsolubilità
References in periodicals archive ?
The need to consistently recreate uniform particle sizing techniques is growing to meet demand for newly developed active pharmaceutical ingredients with poor aqueous solubility well-suited for semi-solid dosage forms.
The therapeutic efficacy of curcumin after it is consumed is far from satisfactory due to its poor aqueous solubility and limited absorption from the gut.
Each of bactericidally active cationic compounds meets at least one of these conditions: (a) in its salt form it has an aqueous solubility of less than 10% w/v in de ionized water at 20[degrees]C.
Even common chemotherapies including paclitaxel, etoposide, and doxorubicin suffer from poor aqueous solubility.
VST has two proton dissociating groups, a carboxyl group and a tetrazole, in the structure, and these parts contribute to the aqueous solubility [12, 13].
Despite the promising pharmacological effects and safety of berberine, poor oral absorption due to its extremely low aqueous solubility results in poor oral systemic bioavailability.
Moreover, API molecules are becoming increasingly complex, tending to reduce aqueous solubility, in turn reducing bioavailability and often leading to difficulties in crystallisation.
DEVELOPMENT OF DRUG SUBSTANCES WITH poor aqueous solubility has become more common, presenting formulators and manufacturing experts with significant new challenges.
As a result of the modern 'high throughput' approach to drug discovery, it has been estimated that up to 70% of the new chemical entities (NCEs) entering drug development programmes possess insufficient aqueous solubility to allow adequate and consistent gastrointestinal (GI) absorption to ensure efficacy.
Thus they provide the formulator with a wide-range of options to meet the challenges of the newer NCEs with very low aqueous solubility.