arenavirus


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Related to arenavirus: bunyavirus

ar·e·na·vi·rus

 (ăr′ə-nə-vī′rəs, ə-rē′nə-)
n.
Any of a family of single-stranded RNA viruses that cause chronic infections in rodents and when transmitted to humans cause various hemorrhagic diseases, including Lassa fever.

[Latin arēna, sand; see arena, virus (so called because when an arenavirus virion is viewed in cross section under an electron microscope, the ribosomes acquired from the host cell appear as fine granules ).]

ar•en•a•vi•rus

(ˌɑr ɛnˈeɪˌvaɪ rəs)
n., pl. -rus•es.
any of various RNA-containing viruses of the family Arenaviridae, usu. transmitted to humans by contact with excreta of infected rodents.
[1971; earlier arenovirus (1970) < Latin (h)arēn(a) sand + -o- + virus; so called from the RNA granules seen in cross sections of the virion]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.arenavirus - animal viruses belonging to the family Arenaviridae
Junin virus - the RNA virus that causes Argentine hemorrhagic fever; carried by rats and mice
Lassa virus - the RNA virus that causes Lassa fever
lymphocytic choriomeningitis virus - the RNA virus that causes lymphocytic choriomeningitis; infects mice and monkeys and dogs and guinea pigs and human beings
Machupo virus - the RNA virus that causes Bolivian hemorrhagic fever; carried by rats and mice
Arenaviridae - a family of arborviruses carried by arthropods
animal virus - an animal pathogen that is a virus
References in periodicals archive ?
(NASDAQ: HOOK, 'HOOKIPA'), a company developing a new class of immunotherapeutics targeting infectious diseases and cancers based on its proprietary arenavirus platform, today announced that HOOKIPA's management team will present and host one-on-one meetings at the following investor conferences in September.
The MACV-GP, which is from an unrelated arenavirus prevalent only in South America, was included as a negative control.
In addition, Hookipa plans to apply its arenavirus platform to develop additional novel immuno-oncology product candidates.
It is an interferon inducible transmembrane protein that provides innate immune response activity by inhibiting members of the retrovirus, filovirus, arenavirus, and herpesvirus families [25].
Decoding arenavirus pathogenesis: Essential roles for alpha-dystroglycan-virus interactions and the immune response.
(28) No agents are approved for the treatment of arenavirus infections besides ribavirin with toxicity concerns.
The relevance of this intriguing mechanism of viral entry is further reinforced by recent work on Lassa virus, an Old World Arenavirus that, similarly to Ebola virus, causes severe to fatal hemorrhagic disease in humans [48, 136].
Finalmente, la epidemia actual de fiebre Lassa en Nigeria, causada por un Arenavirus, ha mostrado una letalidad muy alta, del 54 por ciento, habiendose ya extendido a paises vecinos.
Dai, Discovery and Optimization of Potent Broad-Spectrum Arenavirus Inhibitors Derived From Benzimidazole and Related Heterocycles, Bioorg.