(redirected from arenaviruses)
Also found in: Thesaurus, Medical.


 (ăr′ə-nə-vī′rəs, ə-rē′nə-)
Any of a family of single-stranded RNA viruses that cause chronic infections in rodents and when transmitted to humans cause various hemorrhagic diseases, including Lassa fever.

[Latin arēna, sand; see arena, virus (so called because when an arenavirus virion is viewed in cross section under an electron microscope, the ribosomes acquired from the host cell appear as fine granules ).]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(ˌɑr ɛnˈeɪˌvaɪ rəs)
n., pl. -rus•es.
any of various RNA-containing viruses of the family Arenaviridae, usu. transmitted to humans by contact with excreta of infected rodents.
[1971; earlier arenovirus (1970) < Latin (h)arēn(a) sand + -o- + virus; so called from the RNA granules seen in cross sections of the virion]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.arenavirus - animal viruses belonging to the family Arenaviridae
Junin virus - the RNA virus that causes Argentine hemorrhagic fever; carried by rats and mice
Lassa virus - the RNA virus that causes Lassa fever
lymphocytic choriomeningitis virus - the RNA virus that causes lymphocytic choriomeningitis; infects mice and monkeys and dogs and guinea pigs and human beings
Machupo virus - the RNA virus that causes Bolivian hemorrhagic fever; carried by rats and mice
Arenaviridae - a family of arborviruses carried by arthropods
animal virus - an animal pathogen that is a virus
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
References in periodicals archive ?
Comprehensive panel of real-time TaqMan polymerase chain reaction assays for detection and absolute quantification of filoviruses, arenaviruses, and New World hantaviruses.
LHF-535 is an oral antiviral with potent activity against Lassa fever and other arenaviruses, as demonstrated in preclinical studies.
This is evident that arenaviruses are reemerging in African countries due to climatic or ecological changes and sometimes resulting in case fatalities.
Proper glycosylation of a-DG is also essential for its function as a receptor for lymphocytic choriomeningitis virus, Lassa fever virus, and clade C New World arenaviruses.[24]
Many of arenaviruses are known to cause severe diseases in human.
Notwithstanding, the identification of the receptors for some of the most prominent pathogens, such as the severe acute respiratory syndrome coronavirus (SARS-CoV) or the New World Arenaviruses, was made utilizing standard immunoprecipitation techniques [56, 57].
Like other arenaviruses, Lassa virus is rodent-borne with the multimammate rat (Mastomys natalensis) the primary reservoir and vector of the disease.
Andrew Buckley, PhD Student, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, who is working on a group of haemorrhagic fever viruses called arenaviruses, trying to identify pathways for therapy, worked with International Medical Corps IMC in Makeni, Sierra Leone, in lab diagnostics.
The product is an RNA dependent-RNA polymerase inhibitor that has indicated broad-spectrum activity in vitro against more than 20 RNA viruses in nine different families, such as filoviruses, togaviruses, bunyaviruses, arenaviruses, paramyxoviruses, coronaviruses and flaviviruses.
Viral isolation studies have characterized a divergent arenavirus associated with the disease that has envelope glycoproteins more similar to those of filoviruses than to those of other arenaviruses. (14)