There was nothing on the walls but the paper, an expanse of arsenical
green, soiled with indelible smudges here and there, and with stains resembling faded maps of uninhabited continents.
They are poikiloderma like amyloidosis, xeroderma pigmentosum, dyschromic universalis hereditaria (DUH), acral reticulate pigmentation of Dohi, chronic radiodermatitis, dyskeratosis congenita, arsenical
hyperkeratosis and drug-induced dyschromia due to mono-benzyl ether of hydroquinone, tetracycline, DPCP, thiazides and afloqualone.
Key words Arsenical
neuropathy--arsenicosis--chronic arsenic toxicity--COPD--keratosis--pigmentation--treatment of arsenicosis
(1,5) There is no association between KPPC and arsenical
agents or syphilis.
In fish and most shellfish, the predominant arsenical
is arsenobetaine, the nontoxic nature of which has been clearly established (4, 5).
Plagued by hordes of hungry Colorado beetles, North American farmers resorted to large-scale applications of Paris-green - an arsenical
compound used to colour most green paints - in the late 1860s.
In one study 20.6% persons in Bangladesh and 9.8% persons in West Bengal living in arsenic- affected districts were found to show dermatological features of arsenicosis11 and in a study conducted in the arsenic-prevalent districts of Bangladesh all the patients suffering from arsenicosis showed pigmentary changes.12 Prolonged ingestion of arsenic results in arsenical
hyperkeratosis which appears predominantly on the palms and soles and it has been found that keratosis on the soles is the most sensitive marker for the detection of arsenicosis at an early stage.
* In many of these areas, epidemics of chronic arsenicosis have occurred with arsenical
skin conditions such as melanosis; leukomelanosis ('raindrops on a dusty road') pigmentation changes; and hyperkeratosis, particularly on the palms of the hands and soles of the feet.
Yong Cai of Florida International University spoke about the use of arsenical
pesticides and added that the same difficulty lies in trying to determine the extent of arsenic mobility and ecotoxicity in an open system.