Microscopically, the lungs revealed arteriolar
thickening consisting of medial hypertrophy and intimal fibroplasia.
Effects of endothelium-derived nitric oxide on peripheral arteriolar
tone in man.
However, autoinflammatory mediated injury within the arachnoid villi and the resultant decrease in cerebrospinal fluid absorption and/or thrombotic, vasculitic obliteration of cerebral arteriolar
and venous systems are among the most probable mechanisms.
PerClot is intended for use in clean surgical procedures as an adjunctive hemostatic device when control of capillary, venular, and arteriolar
bleeding by pressure, ligature and other conventional procedures is ineffective or impractical.
16) has shown that afferent arteriolar
vascular resistance is increased and efferent arteriolar
resistance is decreased in DOCA-salt hypertensive rats.
Pathophysiology of drug-induced nephropathy Level of the nephron Action Drugs Preglomerular Afferent arteriolar
Cyclosporine (afferent arteriole) constriction Glomerulus Decreased GFR NSAIDs (prostaglandins) Gold, NSAIDs Glomerulonephritis Penicillamine, cisplatin Proximal tubules Acute tubular necrosis Aminoglycosides, radiocontrast dyes Distal tubules Renal tubular ACE inhibitors, acidosis type 4 cyclosporine Tubules and ducts Crystalluria Acyclovir, sulphonamide Interstitium Interstitial nephritis Penicillin, allopurinol Renal papilla Papillary necrosis NSAIDs, analgesics Table 2.
In pregnancy-induced hypertensive retinopathy, 60% of women will develop retinal arteriolar
spasm and narrowing.
7) While the blood-brain barrier protects the brain from high systemic cholesterol levels, without an optimal transport system of high-density lipids (HDL) to remove excess low-density lipids (LDL) from the body, the gradual deposition of fat in tissue results in arteriolar
narrowing, risking chronic cerebral oxygen deprivation.
2009), narrower retinal arteriolar
diameter (Adar et al.
Laser therapy stimulates cell metabolism, increases blood supply via capillary and arteriolar
vasodilatation, and increases pain threshold in algotrophic nerve fibers and results in analgesic effects (32).
Specifically, ATII causes increased sympathetic activity, sodium reabsorption and water retention, and arteriolar
vasomotor changes during attacks have also been shown in HaNDL patients on MRI (13).