On the other hand, the synthesis and investigation of novel poly(aryl
ether ketone)s would be very useful for a more rigorous structure-property correlation of this very interesting class of polymers.
Among the topics are the copper-catalyzed formation of carbon-phosphorous bonds with aryl
halides, insights into the mechanism of modern Ullmann-Goldberg coupling reactions, copper-catalyzed alkynylation and alkenylation reactions of alkynyl derivatives, applying copper-mediated carbon-nitrogen bond formation in complex molecule synthesis, and reusable catalysts for copper-mediated cross-coupling reactions under heterogeneous conditions.
The palladium-catalyzed Suzuki coupling reaction between aryl
halides and organoboronic acid is an excellent method for the synthesis of various biaryl compounds, which constitute a wide range of fine chemicals, pharmaceuticals, and advanced materials [6-10].
Wheatish light brown crystals, Yield (2.2 g, 85%), m.p 200-204[degrees]C, IR (KBr, [v.sub.max] in [cm.sup.-1]): 3435 (-NH), 2922 (=C-H), 1683 (C=N), 1620 (C=C), [sup.1]H NMR (DMSO-[d.sub.6], 400 MHz) [delta] ppm: 2.5 (s, 2H, -C[H.sub.2]), 72-74 (d, 1H, -C=CH, [J.sub.H-H] = 16.4 Hz), 75-73 (m, 4 aryl
, 3 phenyl protons), 7.8-8.0 (d, 1H, -CH=C, [J.sub.H-H] = 16.4 Hz), 10.0 (s, 1H, -NH of benzimidazole), [sup.13]C NMR (DMSO-[d.sub.6], 100 MHz) [delta] ppm: 102.29, 108.54, 109, 122, 124, 128, 130, 132, 134, 138, 148, 152 (1 dioxymethylene carbon, 6 aryl
carbons, 6 phenylic carbons, 2 vinylic carbons and 1 imidazole quaternary carbon), MS (m/z): 265.10 ([M.sup.+*]), Anal.
In the latter case the N-aryl moiety reacted and gave isopropyl 3-hydroxycarbanilate by photosubstitution of aryl
chlorine with a hydroxyl group [12, 14].
The ROC fraction was measured as the amount of poly-aryl carbon existing in addition to any aryl
C that could be defined as lignin.
In their new approach, the team added compounds that modulate the aryl
hydrocarbon receptor (AhR) pathway.
The Sonogashira cross-coupling reaction takes place between aryl
halide (ArX) and terminal acetylene, catalysed by a zerovalent palladium catalyst to produce diyne (see Fig.
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a widespread environmental pollutant that induces hepatotoxicity through the aryl
hydrocarbon receptor (AhR), although the underlying mechanisms are poorly understood.
At its core, a Buchwald-Hartwig amination is an aryl
halide reacting with an amine [see above example].
The crude was then purified by chromatographic column using n-hexane/AcOEt 2:1 as eluent (yield: 85%); [sup.1]H-NMR (400 MHz, CD[Cl.sub.3]) [delta] 1.34 (s, 9H, Boc); 4.00-4.06(m, 5H, H-1, H-2, and H-3); 4.89 (bs, NHBoc); 7.31 (d, J = 8 Hz, 4H, aryl
); 7.71 (d, 4H, aryl
hydrocarbon receptor (AhR) is a ligand-activated member of the basic-helix-loop-helix family of transcription factors that acts as a sensor for a wide variety of environmental air pollutants, including polycyclic aryl
hydrocarbons (PAHs) [1-3].