In the study, published in the journal Nature, the findings showed that limiting amino acid asparagine
in laboratory mice with triple-negative breast cancer dramatically reduced the ability of the cancer to travel to distant sites in the body.
the team discovered that the appearance of asparagine
synthetase -- the enzyme cells used to make asparagine
-- in a primary tumour was strongly associated with later cancer spread.
is an amino acid, a building block of protein, and
G13013A), resulting in change of amino acid serine to asparagine
Cultures Prepared in solid media supplemented with urea, glutamine (Gln), glutamate (Glu), yeast extract (YE), sodium nitrate (SN), Ammonium sulfate (AS), and asparagine
content of the plantain powder was determined by LC-MS using an enzymatic kit (EZ:faast kit packaging for amino acid analysis, Phenomenex, Torrance, USA).
After storage, the labs tested the potatoes for their levels of reducing sugars and asparagine
The 10-min and the 20-min soak treatments may liberate reducing sugars and asparagine
necessary for production of acrylamide, leading to higher acrylamide concentrations in these treatments.
In this study, the result of screening test revealed that asparaginase producing bacteria were able to hydrolyse L-asparagine
since they utilized L- asparagine
as their substrate and breakdown asparagine
to L-aspartate and ammonia which further reacts with water to produce NH4OH, hence the pH of the medium is basic which subsequently changes the medium from yellow to pink, hence the pinkish zone observed around the colony of asparaginase producing bacteria.
These ESTs were highly homologous with expansion, b-xyloglucan endotransglycosylase, acyl-CoA-binding protein, asparagine
synthetase, seed storage protein, lignin-related peroxidase, cytochrome P450, polyubiquitin, translation initiation factor, and nutrient storage protein.
Asparaginase, an enzyme catalyzing the hydrolysis of asparagine
to aspartic acid and ammonia has attracted huge attention due to its usage against lymphocytic leukemia and different other kinds of cancer affecting man (Krasotkina et al, 2004; Makky et al, 2013).
7 IT CONTAINS high levels of the amino acid asparagine
, which serves as a natural diuretic.