Placebo was associated with a significant increase from baseline in body mass index, alanine aminotransferase and aspartate
aminotransferase (0.17 kg/m(2), 3 and 2 U/l, respectively), whereas TGD was not.
Serum iron, total iron binding capacity (TIBC), percentage saturation, body weight, albumin, aspartate
aminotransferase, and hematocrit were monitored at regular intervals for 2.5 yr.
The blend of organic juices and other organic ingredients comprises at least 70% by weight of the follow composition: Pyrus malus (apple) juice, Citrus medica limonum (lemon) juice, Vitis vinfera (white grape) juice, Saccharum officinarum, milk peptides, Aloe barbadensis leaf juice, glycerin, hydroy-propyl starch phosphate, sodium hydroxide, algae extract, sclerotium gum, tocopherol acetate and tocopherol (vitamin E), ascorbyl palmitate (vitamin C), retinyl palmitate (vitamin A), phospholipids, magnesium aspartate
, zinc gluconate, copper gluconate, phenoxyethanol, benzyl alcohol, potassium sorbate, tetrasodium EDTA and xanthan gum.
Laboratory studies revealed an isolated increase in aspartate
aminotransferase (AST) (3) that prompted consultation with a hepatologist.
In the 6 patients seen during the first week of symptoms (acutely ill patients), lymphopenia was present in 67%, thrombocytopenia in 50%, and increase of alanine aminotransferase/ aspartate
aminotransferase in 67%.
aminotransferase and alanine aminotransferase levels greater than 60 U/L were seen in 15%.
Prelox is a clinically tested, patented combination of two ingredients, L-arginine aspartate
, an amino acid that plays an important role in nitric oxide mechanisms in the body, and Pycnogenol, which supports healthy blood vessels.
In men, aspartate
and alanine aminotransferase concentrations at 20-29 IU/L significantly increased the risk of mortality from liver disease, compared with the lowest concentration for either measurement (less than 20 IU/L).
Specialist pharmaceutical company Impax Laboratories (NasdaqGS:IPXL) reported on Wednesday that it has received US Food and Drug Administration (FDA) approval for its Abbreviated New Drug Application (ANDA) for dextroamphetamine saccharate, amphetamine aspartate
monohydrate, dextroamphetamine sulfate and amphetamine sulfate (mixed salts of a single-entity amphetamine product) extended-release capsules, CII, 5 mg, 10 mg, 15 mg, 20 mg, 25 mg and 30 mg.
Biochemical values measured included serum glucose, sodium, potassium, chloride, magnesium, uric acid, creatine kinase, and aspartate
Laboratory features showed severe anemia (hemoglobin 62 g/L; hematocrit 0.24), with low platelet count (90 x [10.sup.3]/[micro]L) and elevated leukocyte count (130 x [10.sup.3]/[micro]L), together with a moderate increase in liver enzymes (both aspartate
aminotransferase and alanine aminotransferase were more than twice the upper limit of normal values).