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This was the case in the patient we present, an unusual case of a 73-year-old male with an anaplastic astroblastoma.
These histologic and immunohistochemical findings were consistent with a diagnosis of anaplastic astroblastoma.
The immunohistochemical staining pattern was consistent with that observed from the tissue obtained during the stereotactic biopsy, confirming the diagnosis of anaplastic astroblastoma. Adjuvant radiotherapy of 60 gray in 30 fractions was administered to the patient.
The histogenesis of anaplastic astroblastoma is controversial; however tanycytes, glial precursor cells, have been suggested as a potential tissue of origin [14-16].
The treatment of astroblastoma is not well-established owing to its rarity but surgery continues to play a vital role in the management of this condition.
performed a retrospective analysis involving two hundred and thirty-nine patients with astroblastoma and noted a median overall survival of 55 months in patients receiving treatment.
Coakham, "Congenital astroblastoma: an immunohistochemical study.
Rutkowski et al., "Clinical features and post-surgical outcome of patients with astroblastoma," Journal of Clinical Neuroscience, vol.
Velho, "Cerebral astroblastoma: a case report and review of literature," Asian Journal of Neurosurgery, vol.
Chin, "Neuroradiologic characteristics of astroblastoma," Neuroradiology, vol.
Ulu et al., "Supratentorial high grade astroblastoma: report of two cases and review of the literature," Turkish Neurosurgery, vol.
The characteristic papillary architecture and bipartite (astrocytic and neuronal/neurocytic) cell populations distinguish this lesion from other tumors with which it shares histologic features such as dysembryoplastic neuroepithelial tumor, extraventricular neurocytoma, pilocytic astrocytoma, oligodendroglioma, and astroblastoma.
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