atorvastatin


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a·tor·va·stat·in

 (ə-tôr′və-stăt′n)
n.
A statin drug, C33H34FN2O5, that blocks the body's synthesis of cholesterol and is used in its hydrated calcium form to lower cholesterol (especially LDL) levels and to reduce the risk of heart attack and stroke in individuals with elevated risk.

[ator-, of unknown origin + -vastatin, statin suffix; see pravastatin.]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.atorvastatin - an oral drug (trade name Lipitor) that is effective in lowering triglyceridesatorvastatin - an oral drug (trade name Lipitor) that is effective in lowering triglycerides; potent in reducing LDL cholesterol because higher doses can be given
lipid-lowering medication, lipid-lowering medicine, statin, statin drug - a medicine that lowers blood cholesterol levels by inhibiting HMG-CoA reductase
Translations

atorvastatin

n atorvastatina
References in periodicals archive ?
Objectives: To evaluate the effect of Atorvastatin as an adjuvant with betamethasone valerate on disease severity and cardiovascular risks in chronic plaque type psoriatic patients.
In addition to these effects, few studies have shown that statins such as atorvastatin and simvastatin have analgesic and anti-inflammatory activities.
The company, along with the researchers in the clinical trial service unit at the University of Oxford, reported that the product has decreased the risk of major coronary events by 9 percent relative to placebo in the study of 30,449 patients with atherosclerotic vascular disease receiving LDL-C lowering treatment with atorvastatin.
Objective: To obtain pharmacokinetic data of Orvastin, a newly launched formulation of atorvastatin, in healthy males of Pakistan.
The control and hypercholesterolemic rats were divided equally into eight groups such that there was a control group (SCD), control + atorvastatin 20mg/kg (SCD + AV), control + OLE 50mg/kg (SCD + OLE50), control + OLE 100mg/kg (SCD + OLE100), a HCD group (HCD), HCD + atorvastatin 20mg/kg (HCD + AV), HCD + OLE 50mg/kg (HCD + OLE50) and a HCD + OLE 100mg/kg (HCD + OLE100) group.
Adding ezetimibe to atorvastatin boosted the regression of coronary plaque in patients with elevated cholesterol who had just undergone percutaneous coronary intervention (PCI) for acute coronary syndromes or stable angina.
MANCHESTER, ENGLAND -- Results of the Trial of Atorvastatin for the Primary Prevention of Cardiovascular Events in Patients with Rheumatoid Arthritis (TRACE-RA) suggest that daily treatment with atorvastatin may have a primary protective effect on the development of cardiovascular disease in patients with rheumatoid arthritis.
2) Therapy with atorvastatin 80 mg or simvastatin 40 to 80 mg was defined as intensive.
Treatment with atorvastatin, a drug aimed at lowering cholesterol, reduced coronary artery plaque * volume and number in HIV-positive people who took it for 1 year.
Study Selection: Clinical or basic research articles on atorvastatin were included.
We hypothesized that atorvastatin treatment would reduce arterial PWV and that this beneficial vascular effect would be enhanced in physically active adults.
Published in Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy; a new report compared the effects of an aqueous extract of Phyllanthus emblica (Emblica officinalis, amla) versus those of the prescription drug atorvastatin and placebo on endothelial dysfunction and biomarkers of oxidative stress in patients with type II diabetes.