atorvastatin


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a·tor·va·stat·in

 (ə-tôr′və-stăt′n)
n.
A statin drug, C33H34FN2O5, that blocks the body's synthesis of cholesterol and is used in its hydrated calcium form to lower cholesterol (especially LDL) levels and to reduce the risk of heart attack and stroke in individuals with elevated risk.

[ator-, of unknown origin + -vastatin, statin suffix; see pravastatin.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.atorvastatin - an oral drug (trade name Lipitor) that is effective in lowering triglyceridesatorvastatin - an oral drug (trade name Lipitor) that is effective in lowering triglycerides; potent in reducing LDL cholesterol because higher doses can be given
lipid-lowering medication, lipid-lowering medicine, statin, statin drug - a medicine that lowers blood cholesterol levels by inhibiting HMG-CoA reductase
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
Translations

atorvastatin

n atorvastatina
English-Spanish/Spanish-English Medical Dictionary Copyright © 2006 by The McGraw-Hill Companies, Inc. All rights reserved.
References in periodicals archive ?
In people with or at risk for cardiovascular disease, use of the cholesterol-lowering drug atorvastatin (Lipitor[R]) may improve kidney function and, as a result, may reduce cardiovascular risk, according to recent research.
To investigate the potential risks and benefits of statins in moderate-risk patients with rheumatoid arthritis, researchers designed the Trial of Atorvastatin for the Primary Prevention of Cardiovascular Events in Patients with Rheumatoid Arthritis (TRACE RA), a multi-centre, randomised, double-blind trial comparing the statin atorvastatin with placebo.
Atorvastatin calcium, chemically [R-([R.sup.*],[R.sup.*])]-2-(4-Fluorophenyl)-[beta],[delta]-dihydroxy-5-(1-methylethyl)-3-phenyl [(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid, is an HMG-Co A reductase inhibitor with hypolipidemic properties (Figure 1B).
It has been repeatedly proven that Atorvastatin, an inhibitor of 3-hydroxy-3-methylglutaryl coenzy-me A reductase, reduces the risk of cardiovascular disease in patients with type 2 diabetes regardless of being the primary or secondary prevention1,2.
Atorvastatin is one of most commonly prescribed statins for the prevention of both cardiovascular and cerebrovascular diseases.
We present a case of SINAM manifested in a patient with over ten years of simvastatin use who was recently switched to atorvastatin.
Several statins are now available, with different potencies and drug interactions such as atorvastatin, pitavastatin, simvastatin, and rosuvastatin.
Objectives: To evaluate the effect of Atorvastatin as an adjuvant with betamethasone valerate on disease severity and cardiovascular risks in chronic plaque type psoriatic patients.
[8-10] Atorvastatin and simvastatin are the most frequently used hypolipidemic drugs and are given for longer duration.
The company, along with the researchers in the clinical trial service unit at the University of Oxford, reported that the product has decreased the risk of major coronary events by 9 percent relative to placebo in the study of 30,449 patients with atherosclerotic vascular disease receiving LDL-C lowering treatment with atorvastatin.
In addition, PBMCs were treated with: atorvastatin solution, atorvastatin-medicated dentifrice at different concentrations (1, 5, 10, 50 and 100 [micro]M), and equivalent amounts of dentifrice without atorvastatin at different concentrations or only medium for 4 days at 37[degrees]C and 5 % C[O.sub.2].