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A disease, such as rheumatoid arthritis or type 1 diabetes, resulting from an immune reaction against the body's own cells or tissues.
a disease resulting from a disordered immune reaction in which antibodies are produced that damage components of one's own body.
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|Noun||1.||autoimmune disease - any of a large group of diseases characterized by abnormal functioning of the immune system that causes your immune system to produce antibodies against your own tissues|
myasthenia, myasthenia gravis - a chronic progressive disease characterized by chronic fatigue and muscular weakness (especially in the face and neck); caused by a deficiency of acetylcholine at the neuromuscular junctions
disseminated multiple sclerosis, disseminated sclerosis, MS, multiple sclerosis - a chronic progressive nervous disorder involving loss of myelin sheath around certain nerve fibers
autoimmune diabetes, growth-onset diabetes, IDDM, insulin-dependent diabetes mellitus, juvenile diabetes, juvenile-onset diabetes, ketoacidosis-prone diabetes, ketosis-prone diabetes, type I diabetes - severe diabetes mellitus with an early onset; characterized by polyuria and excessive thirst and increased appetite and weight loss and episodic ketoacidosis; diet and insulin injections are required to control the disease
exophthalmic goiter, Graves' disease - exophthalmos occurring in association with goiter; hyperthyroidism with protrusion of the eyeballs
atrophic arthritis, rheumatoid arthritis, rheumatism - a chronic autoimmune disease with inflammation of the joints and marked deformities; something (possibly a virus) triggers an attack on the synovium by the immune system, which releases cytokines that stimulate an inflammatory reaction that can lead to the destruction of all components of the joint
ankylosing spondylitis, Marie-Strumpell disease, rheumatoid spondylitis - a chronic form of spondylitis primarily in males and marked by impaired mobility of the spine; sometimes leads to ankylosis
discoid lupus erythematosus, DLE - a chronic skin disease occurring primarily in women between the ages of 20 and 40; characterized by an eruption of red lesions over the cheeks and bridge of the nose
Hashimoto's disease - autoimmune disorder of the thyroid gland; most common in middle-aged women
LE, lupus erythematosus - a chronic inflammatory collagen disease affecting connective tissue (skin or joints)
pemphigus - a skin disease characterized by large thin-walled blisters (bullae) arising from normal skin or mucous membrane
autoimmunity - production of antibodies against the tissues of your own body; produces autoimmune disease or hypersensitivity reactions
dermatosclerosis, scleroderma - an autoimmune disease that affects the blood vessels and connective tissue; fibrous connective tissue is deposited in the skin