pernicious anaemia

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Related to autoimmune gastritis: hypochlorhydria, pernicious anemia

pernicious anaemia

n
(Pathology) a form of anaemia characterized by lesions of the spinal cord, weakness, sore tongue, numbness in the arms and legs, diarrhoea, etc: associated with inadequate absorption of vitamin B12
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.pernicious anaemia - a chronic progressive anemia of older adults; thought to result from a lack of intrinsic factor (a substance secreted by the stomach that is responsible for the absorption of vitamin B12)
megaloblastic anaemia, megaloblastic anemia - anemia characterized by many large immature and dysfunctional red blood cells (megaloblasts) in the bone marrow; associated with pernicious anemia
metaplastic anaemia, metaplastic anemia - pernicious anemia in which the various formed elements in the blood are changed
anemia, anaemia - a deficiency of red blood cells
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Translations

pernicious anaemia

n (Med) → perniziöse Anämie
Collins German Dictionary – Complete and Unabridged 7th Edition 2005. © William Collins Sons & Co. Ltd. 1980 © HarperCollins Publishers 1991, 1997, 1999, 2004, 2005, 2007
References in periodicals archive ?
Among other conditions that produce chronic inflammation of gastric mucosa are also autoimmune gastritis and pernicious anemia.
Whereas some authors have suggested that PAM is an acquired process representing a metaplastic change in association with chronic gastritis (1, 3) and autoimmune gastritis, (5) others (4, 6, 7) have raised the possibility of PAM being congenital in nature.
Utility of a laboratory score in the prediction of altered autonomic nervous system function in autoimmune gastritis
pylori-associated gastritis (observed in 5.2% of all cases and in 33.3% of cases of gastritis), autoimmune gastritis with microcarcinoid formation, necrotizing vasculitis, and intestinal metaplasia; neoplasms were identified at laparoscopy in 2 additional cases (0.8%).
Patients with RA included in this study had similar histological findings to the healthy group, although some patients with RA had findings suggestive of glandular atrophy typical of autoimmune gastritis. Atrophic gastritis, a hypochlorhydric condition, has been linked to low bone mass, although we were not able to show a correlation between autoimmune gastritis and decreased BMD in postmenopausal women in a previous study (32,33).
This is the first case report of vitamin B12 deficiency secondary to chronic autoimmune gastritis, presenting with concurrent microangiopathic hemolytic anemia and mesenteric panniculitis.
Toh, "Animal models of human disease: experimental autoimmune gastritis--a model for autoimmune gastritis and pernicious anemia," Clinical Immunology, vol.
It has been reported that its overexpression in the stomach can lead to autoimmune gastritis. Moreover, increased levels of GM-CSF auto-antibodies have also been found in patients with Crohn's disease (6).

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