Role of the AMPK pathway in promoting
autophagic flux via modulating mitochondrial dynamics in neurodegenerative diseases: Insight into prion diseases.
6 Additionally interesting, colchicine also upregulates other proteins involved in the
autophagic clearance of misfolded proteins such as the master regulator Transcription Factor EB (TFEB).
They cover enteroviruses future, Enterovirus receptors and entry, hijacking host functions for translation and RNA replication by enteroviruses, the omics of rhinoviruses, viral population dynamics and sequence space, Enterovirus control of cytoplasmic RNA granules, the
autophagic pathway and Enterovirus infection, and the lipid blueprints of replicating viral genomes.
41) Pancratistatin also induces an
autophagic response in p53-mutant prostate cancer cells that might be due in part to possible down-regulation of Bcl-2 proteins by pancratistatin.
Autophagy involves self-destruction starting with engulfment of cytoplasmic material by the phagophore and sequestration of material to the
autophagic vacuoles, where they are eventually destroyed.
11] Increased
autophagic activity is associated with 50%-60% of tumor cell survival under hypoxic conditions.
Two
autophagic-related genes, the microtubule-associated protein light chain 3 (LC3) and the gamma-amino butyric acid receptor-associated protein (GABARAP), are indispensable for
autophagic process since they anchor the lysosomal membrane to the autophagosome (9,10).
Brucella abortus transits through the
autophagic pathway and replicates in the endoplasmic reticulum of nonprofessional phagocytes.
They used RT-PCR and Western blotting to look for
autophagic and apoptotic changes in cerebral cortex and brainstem gene and protein levels.
Change in intestinal villi, cell area and intracellular
autophagic vacuoles related to intestinal function in chickens.
who found that invasive bacteria induce
autophagic responses via binding of bacterial NOD1 ligand to cellular NOD1 at the bacterial entry site, which then triggers autophagy by NOD1 binding to ATG16L1, an autophagy-inducing protein.
Cellular metabolic and
autophagic pathways: Traffic control by redox signaling.
