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The process of self-digestion by a cell through the action of enzymes originating within the same cell.


(ɔːˈtɒfədʒɪ) or


the consumption of one's own tissue by biting oneself

autophagy, autophagia

Medicine. 1. the eating of one’s own body.
2. the nutrition of the body by its own tissues, as in dieting. — autophagous, adj.
See also: Food and Nutrition
References in periodicals archive ?
Autophagy is a genetically programmed dynamic process for the lysosomal degradation and recycling of bulk cytoplasmic contents, abnormal proteins, and damaged organelles.
Autophagy is a highly regulated process that is responsible for degrading long-lived or aggregated proteins and damaged organelles and is characterized by sequestration of cytoplasmic cargoes into double-membrane vesicles called autophagosomes.
Worms without KLF proteins cannot maintain autophagy and die early.
In a 2017 study, Ju Hwan Kim and Korean colleagues showed that radiofrequency electromagnetic fields (RF-EMF), such as radiation emitted by cell phones, activate autophagy in cerebral cortex neurons and apoptosis in the brainstem cells of mice.
The same mechanism in living organisms that promote health and fitness in young age is responsible for ageing, scientists have found, identifying for the first time the genes responsible for the mechanism called autophagy.
Biologists and other scientists from Europe, Brazil, and China discuss the seven most important bacterial secretion systems, within-host envelope remodeling, subversion of macrophage functions by bacterial protein toxins and effectors, pathogen manipulation of host autophagy, mechanisms involved in sensing and restriction of bacterial replication, mechanisms of evasion by Salmonella, evasion strategies of mycobacteria, and the role of cyclic di-GMP in virulence and evasion of the plant immune system.
The scientists reported their findings online on July 17, 2017 in the journal Autophagy.
Olive oil may fight this by activating the autophagy process and reducing brain inflammation.
They say olive oil activates a process called autophagy, by which cells break down and clear out intracellular debris and toxins.
Autophagy is a catabolic process in which cellular constituents, including proteins, lipids, and even entire organelles, are digested using lysosomal lytic enzymes.
Recently, researchers described the function of autophagy, a cellular recycling process critical for homeostasis, in germline SC proliferation of C.
Autophagy is a natural mechanism that disassembles cells' unnecessary or dysfunctional components as they age and lose their function.