12], Interestingly, hypertension influences the autoregulation
of CBF by narrowing the range of the autoregulatory process instead of its speed, resulting in a steeper CBF-BP curve.
is the ability of a vascular bed to maintain its blood flow despite changes in perfusion pressure.
Endothelial function in the perinatal period played a fundamental role in the autoregulation
of vascular tone and a significant part in the formation of hypoxic brain damage.
This role of GDF11 as negative autoregulation
of cell proliferation is in accordance with the negative role of GDF8 as muscle cell proliferation regulation .
Lowering or increasing mean BP beyond the scope of autoregulation
constitutes a direct risk to life.
It's possible the very elderly have impaired cerebral autoregulation
, especially if there's a history of hypertension.
Structural basis of autoregulation
of phenylalanine hydroxylase.
Also, a person's sitting position, myogenic autoregulation
, and the release of vasodilating chemicals such as nitric oxide (NO), prostaglandins, and adenosine contribute to blood flow and pressure changes in the body (4-6,8,9,19,21,23,27,29,31,35).
Increased cerebral blood flow and the loss of autoregulation
of intracranial pressure may contribute to such an increase.
Objectives: The aim of this study was to investigate the risk of inducing high intracranial pressure (ICP) related to interventions and whether intracranial compliance, baseline ICP, or autoregulation
could be used as predictors.
Recent studies suggest the cerebral blood flow responses to oxygen and carbon dioxide as well as the autoregulation
of blood flow are present in the newborn (22,23); however, the range of autoregulation
is narrow and very close to the limits of normal blood pressure (see Fig.
7,14-16) This has led to a variety of hypotheses for circulatory insufficiency, including nocturnal hypotension and aberrant autoregulation