Also found in: Medical, Wikipedia.


 (ôk′sə-trŏf, -trōf′)
An organism, such as a strain of bacteria, that has lost the ability to synthesize certain substances required for its growth and metabolism as the result of mutational changes.

[Back-formation from auxotrophic.]


(Microbiology) a mutant strain of microorganism having nutritional requirements additional to those of the normal organism
ˌauxoˈtrophic adj
References in periodicals archive ?
Paradoxically, single and double auxotroph strains had lower mean MICs than the 2 nonauxotroph strains.
Culture conditions for the production of L-glutamic acid from n-paraffins by glycerol auxotroph GL-21.
The genome identified the strain B14 as an auxotroph for L-lysine, L-phenylalanine, L-tyrosine, L-trypthopan, L-phenylalanine, L-isoleucine, L-leucine, L-serine and L-valine.
L-Tryptophan production by analog-resistant mutants derived from a phenylalanine and tyrosine double auxotroph of Corynebacterium glutamicum.
Reactive oxygen species are the major antibacterial against Salmonella Typhymurium purine auxotroph in the phagosome of RAW2647.
The present study focused on the development of auxotroph and over production of lysine in stirred tank fermentation, after releasing the various metabolic control mechanism and utilizing three different media.
Differential expression of Met auxotroph, Escherichia coli DL41 (DE3) pCOCK, has revealed proteomic variation in cells forced to use TeMet in the translation of proteins.
For example, auxotroph mutants are easy to maintain and observe on selective media and are strongly selected against on restrictive media (Welden & Hossler, 2003; Krist & Showsh, 2007).
The yeast morphotype but not the mold, for example, has a cysteine dioxygenase activity and is a cysteine auxotroph.
The cysteine auxotroph and the mutant carrying the cloning vector, however, were unable to support the growth in the absence of cysteine (Fig.
One lysine mutant was characterized as an auxotroph on selective media, and the transposon-inserted gene fragment confirmed as incorporated into the chromosome by a Southern blot (N=1).