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Related to auxotrophy: prototrophy, auxotrophs


 (ôk′sə-trŏf′ĭk, -trō′fĭk)
Requiring one or more specific substances for growth and metabolism that the parental organism was able to synthesize on its own. Used with respect to organisms, such as strains of bacteria, algae, or fungi, that can no longer synthesize certain growth factors because of mutational changes.

[Greek auxein, to increase; see auxin + -trophic.]

aux·ot′ro·phy (ôk-sŏt′rə-fē) n.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


the inability to synthesize particular growth factors, due to mutational changes
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References in periodicals archive ?
Murray, "Amino acid auxotrophy as a system of immunological control nodes," Nature Immunology, vol.
fumigatus mutants that exhibit auxotrophy for the three aromatic amino acids are impossible to obtain.
Gilsdorf, "Histidine auxotrophy in commensal and disease-causing nontypeable Haemophilus influenzae," Journal of Bacteriology, vol.
Ascorate abolishes auxotrophy caused by the lack of superoxide dismutase in Saccharomyces Cervesiae.
There is some evidence that genetic safeguards, such as engineered auxotrophy, "kill switches", barriers to gene flow, and "genetic firewalls" can be built into organisms that are constructed using synthetic biology, (194) but there was no discussion in Oversight about how the use of genetic safeguards could be furthered by minimizing the regulation of sNA manufacturing in Canada.