Keywords: Acute inflammatory demyelinating polyneuropathy, Acute motor axonal
neuropathy, Acute motor sensory axonal
neuropathy, Fisher syndrome, Guillain-Barre syndrome.
Effective 1 January 2018, Keller will help achieve the company's goal to pioneer breakthrough disease-modifying therapeutics for patients with neurological diseases by preventing axonal
degeneration, stabilizing disease and allowing for functional recovery.
Disarm Therapeutics, a biotechnology company creating a new class of disease-modifying therapeutics for patients with axonal
degeneration, a central driver of neurological disease, has named Peter Keller as its new chief business officer effective January 1, 2018, it was reported on Tuesday.
On September 19, 2017, Disarm Therapeutics, a new biotechnology company developing therapeutics to treat patients with neurological diseases by preventing axonal
degeneration, announced the recent completion of a $30 million Series A financing.
In the femoral nerve, there was axonal
degeneration with myelin sheath expansion and the presence of vacuoles, usually in chains and containing axonal
debris or macrophages (Figure 2B, 2C and 2D).
damage is the major culprit underlying disability in conditions such as spinal-cord injury (SCI) and stroke.
It begins with chapters on the order of ontogeny, including cell differentiation and neural induction, the development of a body pattern, neurogenesis and neural migration, neural differentiation, axonal
pathfinding, synapse formation, and apoptosis, followed by chapters on activity-guided, experience-guided, and socially guided neural development.
GBS subtypes are recognised on the basis of electrodiagnostic and pathologic distinctions and it included Acute Inflammatory Demyelinating Polyneuropathy (AIDP), the most common variant followed by two axonal
variants-Acute Motor Sensory Axonal
Neuropathy (AMSAN) and Acute Motor Axonal
Nerve conduction study/ electromyogram may be normal or show axonal
motor neuropathy or axonal
The court heard Finley suffered axonal
brain injury - which can lead to coma.
Thus, these studies were indicative of a severe ongoing on chronic denervating process of mainly cranial nerves and length dependent mild axonal
neuropathy in the limbs.
We observed hyperreflexia in the course of the motor axonal
neuropathy form of Guillain-Barre syndrome (GBS).