axonal

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ax·on

 (ăk′sŏn′) also ax·one (-sōn′)
n.
The usually long process of a nerve fiber that generally conducts impulses away from the body of the nerve cell.

[Greek axōn, axis.]

ax′on·al (ăk′sə-nəl, ăk-sŏn′əl) adj.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Adj.1.axonal - of or relating to or resembling an axonaxonal - of or relating to or resembling an axon
neuroscience - the scientific study of the nervous system
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Release date- 23082019 - Cambridge - Disarm Therapeutics, a biotechnology company creating a new class of disease-modifying therapeutics for patients with axonal degeneration, today announced the publication of two articles in Science that significantly advance the understanding of the structure and function of SARM1, a protein that is a critical regulator of cellular degeneration, and provide further support for the centrality of the NAD+-cleavage pathway in mediating cellular degeneration across multiple species.
Alcoholic polyneuropathy is characterized by axonal degeneration and demyelination.
MS is traditionally characterized based on chronic inflammatory demyelinating lesions (4); however, recent studies have reported that axonal degeneration may be prominent in the beginning of the inflammation period of the disease (5,6).
Axonal degeneration was calculated using the following formula: 1-[mV (left)/mV (right)], and latency difference was calculated using the following formula: ms (left)-ms (right).
Consequently, acute axonal degeneration of the common peroneal nerve can be improved secondary to distal ischemia as results of increased pressure inside the compartment with stasis and edema occurring during the application VA-ECMO.
On the 21st day electromyographic examination, "90% of subacute axonal degeneration findings in the right facial nerve" were detected.
By inhibiting the SARM1 protein, identified by the company's scientific founders as the central driver of axonal degeneration, these therapeutics may prevent the loss of axons in chronic and acute diseases of the central, ocular, and peripheral nervous systems.
These were more related to Schwann cell degeneration rather than axonal degeneration. [30]
The peripheral nerve dysfunction was also linked to the morphological evidence of primary axonal degeneration in the form of shrinkage of axons, disintegration of neurotubules and neurofilaments, and active axonal breakdown.
Neighboring cerebellar white matter contained variable amounts of axonal spheroids indicative of axonal degeneration and spongiosis of the neuropil.
During the acute phase before the stage of axonal degeneration, nerve conduction study in necrotizing vasculitis may show a pseudo conduction block adding difficulty in differentiating it from inflammatory neuropathies.