In the distal stump, the cytoskeletal structures (neurofilaments and microtubules) go through disintegration, with accumulation of granular debris in the axoplasm
. The cell membrane disappears, the axon undergoes fragmentation and the myelin rapidly disintegrates.
Tiny mitotic figures and electron-dense granules were detected in the axoplasm
The axon was normal, mitochondria and neuroflaments were prominent in axoplasm
. Degenerated mitochondria and decrease of organelles were observed in Schwann cell.
within a nerve fibre is conmposed of 87% water held together by cytoskeleton .
This may result in ischemic injury, glial cell activation, reduced axoplasm
flow, and neurotrophin deprivation, finally causing RGC apoptosis .
Video microscopy of fast axonal transport in extruded axoplasm
: a new model for study of molecular mechanisms.
The normal, uninjured nerve fibers obtained from rats showed preserved axoplasm
, healthy mitochondrial profiles, and astrocytic processes with regular thicknesses (Figure 2A).
The white centre of Roth spots consist of arrested axoplasm
. Causes of anemia include nutritional deficiency, blood loss, inadequate production of red blood cells or increased destruction of red blood cells (4).
Pant, "Principal neurofilament-associated protein kinase in squid axoplasm
is related to casein kinase I," Journal of Biological Chemistry, vol.
Presence of D-aspartate in squid axoplasm
and in other regions of the cephalopod nervous system.
A build-up of blocked axoplasm
in the optic nerve head becomes visible as a swelling, causing the appearance of papilloedema (Figure 1).
The membrane and inner carinulae in deformed mitochondria were absent, and the neurosecretory particles under transportation in the axoplasm