azathioprine


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Related to azathioprine: prednisone, methotrexate

az·a·thi·o·prine

 (ăz′ə-thī′ə-prēn′)
n.
An immunosuppressive agent used to prevent organ rejection in kidney transplant recipients and to treat severe rheumatoid arthritis.

[Probably from az(o)- + thio- + p(u)rine.]

azathioprine

(ˌæzəˈθaɪəˌpriːn)
n
(Pharmacology) a synthetic drug that suppresses the normal immune responses of the body and is administered orally during and after organ transplantation and also in certain types of autoimmune disease. Formula: C9H7N7O2S
[C20: from aza- + thio- + p(u)rine]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.azathioprine - an immunosuppressive drug (trade name Imuran) used to prevent rejection of a transplanted organazathioprine - an immunosuppressive drug (trade name Imuran) used to prevent rejection of a transplanted organ
medicament, medication, medicinal drug, medicine - (medicine) something that treats or prevents or alleviates the symptoms of disease
Translations

azathioprine

n azatioprina
References in periodicals archive ?
Prednisone, azathioprine, and mycophenolate carried higher risks of serious infections at 6 months than methotrexate or cyclosporine, the authors said.
Azathioprine (AZA) (Immuran, GlaxoSmithKline, Middlesex, UK) was started at a dose of 2-2.5 mg/kg/d at the time of diagnosis or as the maintenance therapy during evaluation for a dose reduction of steroids at 4, 8, or 12 weeks.
The label update was based on data from a Roche-supported study by the French Vasculitis Study Group showing that treatment with the rituximab regimen resulted in fewer major relapses by month 28 compared to treatment with azathioprine. The observed safety profile was consistent with that previously observed in this patient population.
Following pulse therapy, 64 mg oral prednisolone and 150 mg (50 mg 3 times daily) azathioprine were co-administered.
Azathioprine (AZA) still corresponds to the mainstay maintenance therapy in anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides (1, 2).
At symptom onset, she had received infliximab and azathioprine for >5 years and reported eating undercooked meat; she had not traveled abroad.
Azathioprine is an immunosuppressant used in the treatment of various autoimmune conditions, including myasthenia gravis.
Thiopurines, azathioprine (AZA), and 6-mercaptopurine (6MP) have been considered the reference maintenance treatment for patients with steroid-dependent and steroid-refractory moderate-to-severe UC for many years and are recommended as the first line immunosuppressive therapy by major guidelines [1, 5].
Immunomodulators including azathioprine, calcineurin inhibitors, and cyclosporine have been tried with mixed success [8, 16, 17].
1 mg/kg/day oral corticosteroid, 25 mg/day azathioprine, warfarin tailored to international normalized ratio target, 3 tablets/day acetazolamide and 1 tablet/day potassium were started for the patient.