azidothymidine


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Related to azidothymidine: nevirapine

a·zi·do·thy·mi·dine

 (ə-zī′dō-thī′mĭ-dēn′, ə-zē′-, ăz′ĭ-)
n.
See AZT.

azidothymidine

(əˌzaɪdəʊˈθaɪmɪˌdiːn)
n
an antiretroviral drug used to treat HIV/AIDS

AZT


Trademark.
azidothymidine: an antiviral drug used in the treatment of AIDS. Compare zidovudine.
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References in periodicals archive ?
The first drug used in the treatment of HIV was azidothymidine (AZT; zidovudine).
Oral mucosa pigmentation: A new side effect of azidothymidine therapy in patients with acquired immunodeficiency syndrome.
That same year, contrary to the WHO recommendation (29) to use Tenofovir rather than Azidothymidine (AZT) as first-line treatment, because it was "less toxic", this was not implemented in Mozambique, because supply was already being met by provision of partner-donated AZT30.
Subsequently, employing the Cu (I) catalyzed click chemistry, the alkynylated coumarin intermediates were subjected to cycloaddition with the azidothymidine compound (31) to obtain 1,2,3-triazole moieties (32a-e).
Macrocytic anaemia was, however, more common among HIV-infected patients, most likely due to the use of azidothymidine. [23]
the virus entry inhibitor dextran sulfate 5000, the broad antiviral agent ribavirin, the antiherpetic drug ganciclovir, and the HIV inhibitor azidothymidine. After 3-6 days incubation at 37[degrees]C (or 35[degrees]C in the case of INF virus), the cultures were examined by microscopy to score the compounds' inhibitory effect on virus-induced cytopathic effect or their cytotoxicity.
This was not changed with additional azidothymidine, which has been reported to increase the efficiency for NHEJ [25] (not shown).
Grieco et al., "The efficacy of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex.
have also proven that EGCG inhibit reverse transcriptase and act synergistically with another reverse transcriptase inhibitor, namely, azidothymidine [96].
Other examples of substances of particular public interest about which NTP provided critical research findings include AZT (azidothymidine) and a number of drug combinations used to prevent mother-to-child transmission of HIV (human immunodeficiency virus); fluoride; polychlorinated biphenyls; hexavalent chromium; acrylamide; silicone fluid used in breast implants; and phenolphthalein, which was once used in laxatives.
He was the guinea pig, one of many who took the first HIV drug: AZT (azidothymidine), which was fast-tracked by the FDA in 1987 as thousands were dying.
The management of HIV/AIDS, which involves medications such as Azidothymidine (AZT), has been reported to have adverse effect on the auditory function of individuals infected with HIV/AIDS.