Cresemba, an intravenous and oral azole
antifungal and the active agent of the prodrug isavuconazonium sulfate, was approved in March 2015 by the United States Food and Drug Administration for patients 18 years of age and older in the treatment of invasive aspergillosis and invasive mucormycosis.
Open Competition: Research and development work on the theme: "Development and production of prototypes of the finished dosage form of the drug based on the substance of a number of compounds azole
This is a first-in-class azole
antifungal for the treatment of pulmonary aspergillosis, including fungal asthma, pulmonary aspergilloma, aspergillus infections in lung transplant recipients and patients with cystic fibrosis.
After determination of the MIC of each drug alone, (10) dilutions were prepared in order to obtain four-fold the final concentrations: 50 mL- aliquots of each azole
dilution were combined with other 50 mL of either amphotericin B or terbinafine dilutions.
An experiment was designed to compare the dimensional stability of flat decking to ribbed decking using three copper-based preservatives: alkaline copper quat (ACQ-D), copper azole
(CA), and chromated copper arsenate (CCA).
Successful treatment often requires only excision, although an azole
is sometimes also given.
After clinical diagnosis and microscopic confirmation, tinea cruris is best treated with a topical allylamine or an azole
antifungal (strength of recommendation: A, based on multiple randomized controlled trials [RCTs]).
The oral presentation describes the results of a study designed to evaluate the in vivo efficacy of SCY-078 in combination with isavuconazole, an azole
used for the treatment of invasive pulmonary aspergillosis.
Isavuconazole is an intravenous and oral azole
antifungal for the treatment of life-threatening invasive mould infections.
Approximately half of respondents were aware that azole
resistance of A.
Contract Awarded for Azole
resistance in agricultural settings